Product Name: S-Ruxolitinib (INCB018424)
Subtitle: JAK1/2 inhibitor,potent and selective
Biological Activity: Biological Activity of S-Ruxolitinib (INCB018424)Description S-Ruxolitinib is the chirality of INCB018424. Targets JAK1 JAK2 JAK3 IC50 3.3 nM 2.8 nM 428 nM
SMLES: C1CCC(C1)C(CC#N)N2C=C(C=N2)C3=C4C=CNC4=NC=N3
CAS NO: 606101-58-0
Standard In CHIKey: NOD-like Receptor NLR) inhibitors
Standard InChI:
Typrof Compound:
Appearance:
Formula: C17H18N6
M.Wt: 306.37
General Tips: For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.PubMed ID:http://jpet.aspetjournals.org/content/253/3/1090
Shipping Condition: Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other courier with RT , or blue ice upon request.
Solubility: Soluble in DMSO > 10 mM
Storage:
Purity: >98%
Chemical Name: (3S)-3-cyclopentyl-3-[4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)pyrazol-1-yl]propanenitrile