Product Name: SB-334867 free base
Subtitle: orexin-1 receptor antagonist, selective
Biological Activity: Biological Activity of SB-334867 free baseSelective non-peptide orexin OX1 receptor antagonist. pKb values are 7.2 and < 5 for inhibition of intracellular Ca2+ release in CHO cells expressing human OX1 and OX2 receptors respectively. Blocks orexin-A in
SMLES: CC1=NC2=C(O1)C=C(C=C2)NC(=O)NC3=C4C(=NC=C3)C=CC=N4
CAS NO: 307983-31-9
Standard In CHIKey: KLF inhibitors
Standard InChI:
Typrof Compound:
Appearance:
Formula: C17H13N5O2
M.Wt: 319.32
General Tips: For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.PubMed ID:http://jpet.aspetjournals.org/content/263/1/158
Shipping Condition: Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other courier with RT , or blue ice upon request.
Solubility: Soluble to 100 mM in DMSO with gentle warming and to 10 mM in ethanol with gentle warming
Storage: Desiccate at RT
Purity: >98%
Chemical Name: N-(2-Methyl-6-benzoxazolyl)-N-1,5-naphthyridin-4-yl urea