Product Name: SB408124
Subtitle: OX(1)receptor antagonist
Biological Activity: Biological Activity of SB408124Selective non-peptide orexin OX1 receptor antagonist (Kb values are 21.7 and 1405 nM for human OX1 and OX2 receptors respectively). Blocks orexin-A induced grooming following oral administration in vivo.
SMLES: CC1=NC2=C(C=C(C=C2C(=C1)NC(=O)NC3=CC=C(C=C3)N(C)C)F)F
CAS NO: 117048-59-6
Standard In CHIKey: FLAP inhibitors
Standard InChI:
Typrof Compound:
Appearance:
Formula: C19H18F2N4O
M.Wt: 356.38
General Tips: For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.PubMed ID:http://jpet.aspetjournals.org/content/262/3/929
Shipping Condition: Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other courier with RT , or blue ice upon request.
Solubility: Soluble to 100 mM in DMSO
Storage: Store at RT
Purity: >98%
Chemical Name: N-(6,8-Difluoro-2-methyl-4-quinolinyl)-N-[4-(dimethylamino)phenyl]urea