Product Name: SGI-110
Subtitle: DNA methyltransferases inhibitor,potent
Biological Activity: Biological Activity of SGI-110Description SGI-110 is a dinucleotide antimetabolite of decitabine linked via phosphodiester bond to a guanosine Targets DNA Methyltransferase IC50
SMLES: C1C(C(OC1N2C=NC3=C2NC(=NC3=O)N)COP(=O)(O)OC4CC(OC4CO)N5C=NC(=NC5=O)N)O
CAS NO: 84573-16-0
Standard In CHIKey: MAPKAPK2 MK2) inhibitors
Standard InChI:
Typrof Compound:
Appearance:
Formula: C18H24N9O10P
M.Wt: 557.41
General Tips: For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.PubMed ID:http://jpet.aspetjournals.org/content/253/3/1189
Shipping Condition: Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other courier with RT , or blue ice upon request.
Solubility: Soluble in DMSO
Storage:
Purity: >98%
Chemical Name: [(2S,3R,5R)-5-(2-amino-6-oxo-3H-purin-9-yl)-3-hydroxyoxolan-2-yl]methyl [5-(4-amino-2-oxo-1,3,5-triazin-1-yl)-2-(hydroxymethyl)oxolan-3-yl] hydrogen phosphate