Product Name: SU 9516
Subtitle: Cdk2 inhibitor
Biological Activity: Biological Activity of SU 9516Potent, selective cdk2 inhibitor (IC50 values are 0.022, 0.04, 0.2, >10, >10, 18 and >100 μM for cdk2, cdk1, cdk4, PKC, p38, PDGFR and EGFR respectively). Inhibits pRb phosphorylation causing enhanced pRB/E2F
SMLES: COC1=CC2=C(C=C1)NC(=O)C2=CC3=CN=CN3
CAS NO: 1542705-92-9
Standard In CHIKey: Farnesyl Transferase inhibitors
Standard InChI:
Typrof Compound:
Appearance:
Formula: C13H11N3O2
M.Wt: 241.25
General Tips: For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.PubMed ID:http://jpet.aspetjournals.org/content/252/1/235
Shipping Condition: Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other courier with RT , or blue ice upon request.
Solubility: Soluble to 100 mM in DMSO and to 20 mM in ethanol
Storage: Store at +4℃
Purity: >98%
Chemical Name: (Z)-1,3-Dihydro-3-(1H-imidazol-4-ylmethylene)-5-methoxy-2H-indol-2-one