Product Name: UNC1215
Subtitle: Chemical probe for the methyllysine (Kme)
Biological Activity: Biological Activity of UNC1215Description Ko 143 is a potent inhibitor of L3MBTL3 methyllysine (Kme) reader domain with an IC50 value of 40 nM and Kd value of 120 nM. Targets L3MBTL3 L3MBTL3- D274A IC50 40 nM (Kd=120 nM) 3.5 μM
SMLES: C1CCN(C1)C2CCN(CC2)C(=O)C3=CC(=C(C=C3)C(=O)N4CCC(CC4)N5CCCC5)NC6=CC=CC=C6
CAS NO: 174022-42-5
Standard In CHIKey: GPR40 inhibitors
Standard InChI:
Typrof Compound:
Appearance:
Formula: C32H43N5O2
M.Wt: 529.72
General Tips: For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.PubMed ID:http://jpet.aspetjournals.org/content/253/2/729
Shipping Condition: Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other courier with RT , or blue ice upon request.
Solubility: Soluble in DMSO > 10 mM
Storage:
Purity: >98%
Chemical Name: [3-anilino-4-(4-pyrrolidin-1-ylpiperidine-1-carbonyl)phenyl]-(4-pyrrolidin-1-ylpiperidin-1-yl)methanone