Product Name: Varlitinib (ARRY334543)
Subtitle: ErbB inhibitor
Biological Activity: Biological Activity of Varlitinib (ARRY334543)Description Varlitinib is a selective and potent inhibitor of ErbB1(EGFR) and ErbB2(HER2) with IC50 values of 7 nM and 2 nM, respectively. Targets ErbB2 ErbB1 IC50 2 nM 7 nM
SMLES: CC1COC(=N1)NC2=CC3=C(C=C2)N=CN=C3NC4=CC(=C(C=C4)OCC5=NC=CS5)Cl
CAS NO: 1627503-67-6
Standard In CHIKey: Anti-infection_Compound_Library inhibitors
Standard InChI:
Typrof Compound:
Appearance:
Formula: C22H19ClN6O2S
M.Wt: 466.94
General Tips: For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.PubMed ID:http://jpet.aspetjournals.org/content/254/3/888
Shipping Condition: Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other courier with RT , or blue ice upon request.
Solubility: Soluble in DMSO > 10 mM
Storage:
Purity: >98%
Chemical Name: 4-N-[3-chloro-4-(1,3-thiazol-2-ylmethoxy)phenyl]-6-N-[(4R)-4-methyl-4,5-dihydro-1,3-oxazol-2-yl]quinazoline-4,6-diamine