Product Name: XL413 hydrochloride
Subtitle: Cdc7 inhibitor
Biological Activity: Biological Activity of XL413 hydrochloridePotent and selective Cdc7 inhibitor (IC50 = 3.4 nM). Exhibits >12-fold selectivity for Cdc7 over PIM-1 kinase and >30-fold selectivity over pMCM and CK2. Inhibits proliferation of Colo 205 cells in vitro
SMLES: C1CC(NC1)C2=NC(=O)C3=C(N2)C4=C(O3)C=CC(=C4)Cl.Cl
CAS NO: 187227-45-8
Standard In CHIKey: Thrombin inhibitors
Standard InChI:
Typrof Compound:
Appearance:
Formula: C14H13Cl2N3O2
M.Wt: 326.18
General Tips: For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.PubMed ID:http://jpet.aspetjournals.org/content/252/1/51
Shipping Condition: Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other courier with RT , or blue ice upon request.
Solubility: Soluble to 20 mM in water
Storage: Store at -20℃
Purity: >98%
Chemical Name: 8-Chloro-2-(2S)-2-pyrrolidinylbenzofuro[3,2-d]pyrimidin-4(3H)-one hydrochloride