Product Name: Zebularine
Subtitle: DNA methylation inhibitor
Biological Activity: Biological Activity of ZebularineOrally active DNA methyltransferase inhibitor. Inhibits tumor cell proliferation (IC50 = 120 μM) and re-activates silenced genes in T24 bladder carcinoma cells. Inhibits cytidine deaminase (Ki ~ 2 μM); induces differ
SMLES: C1=CN(C(=O)N=C1)C2C(C(C(O2)CO)O)O
CAS NO: 211110-63-3
Standard In CHIKey: RPQZTTQVRYEKCR-UHFFFAOYSA-NAdenylate Cyclase inhibitors
Standard InChI: InChI=1S/C9H12N2O5/c12-4-5-6(13)7(14)8(16-5)11-3-1-2-10-9(11)15/h1-3,5-8,12-14H,4H2
Typrof Compound:
Appearance:
Formula: C9H12N2O5
M.Wt: 228.2
General Tips: For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.PubMed ID:http://jpet.aspetjournals.org/content/253/2/545
Shipping Condition: Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other courier with RT , or blue ice upon request.
Solubility: Soluble to 100 mM in water and to 100 mM in DMSO
Storage: Desiccate at RT
Purity: >98%
Chemical Name: 1-β-D-Ribofuranosyl-2(1H)-pyrimidinone