AZ3146
Product Name: AZ3146Subtitle: Mps1 inhibitor,potent and selectiveBiological Activity: Biological Activity of AZ3146Potent and selective monopolar spindle 1 (Mps1) kinase inhibitor (IC50 = 35 nM). Displays selectivity over 46 other kinases…
Palbociclib (PD0332991) Isethionate
Product Name: Palbociclib (PD0332991) IsethionateSubtitle: CDK4/6 inhibitor,highly selectiveBiological Activity: Biological Activity of Palbociclib (PD0332991) IsethionateDescription Palbociclib (PD0332991) Isethionate is a highly selective inhibitor of CDK4/6 with IC50 of 11 nM/16…
AZD-5438
Product Name: AZD-5438Subtitle: Potent CDK1/2/9 inhibitorBiological Activity: Biological Activity of AZD-5438Potent inhibitor of cyclin-dependent kinase (cdk) 1, 2 and 9 (IC50 values are 16, 6 and 20 nM respectively). Exhibits…
PD 0332991 (Palbociclib) HCl
Product Name: PD 0332991 (Palbociclib) HClSubtitle: CDK4/6 inhibitor,highly selectiveBiological Activity: Biological Activity of PD 0332991 (Palbociclib) HClDescription Palbociclib (PD-0332991) HCl is a highly selective inhibitor of CDK4/6 with IC50 of…
ZCL278
Product Name: ZCL278Subtitle: Selective Cdc42 inhibitorBiological Activity: Biological Activity of ZCL278Selective inhibitor of Cdc42. Targets the binding site of the Cdc42 guanine nucleotide exchange factor, intersectin (ITSN). Inhibits Cdc42-mediated cellular…
AZD7762
Product Name: AZD7762Subtitle: Checkpoint kinase inhibitor,ATP competitiveBiological Activity: Biological Activity of AZD7762Description AZD7762 is a potent and selective inhibitor of Chk1 with IC50 of 5 nM. Targets CHK1 CHK2 IC50…
MK-1775
Product Name: MK-1775Subtitle: Wee1 kinase inhibtor,potent and ATP-competitiveBiological Activity: Biological Activity of MK-1775Description MK-1775 is a potent and selective inhibitor of Wee1 with IC50 of 5.2 nM. Targets Wee1 IC50…
AT7519
Product Name: AT7519Subtitle: Multi-CDK inhibitorBiological Activity: Biological Activity of AT7519Description AT7519 is a inhibitor of CDK1, 2, 4, 5, 6 and 9 with IC50 values of 10-210 nM. Targets CDK9/CyclinT…
BS-181 HCl
Product Name: BS-181 HClSubtitle: CDK7 inhibitor,highly selectiveBiological Activity: Biological Activity of BS-181 HClDescription BS-181 HCl is a highly selective inhibitor of CDK7 with an IC50 value of 21 nM. Targets…
PHA-793887
Product Name: PHA-793887Subtitle: Pan-Cdk inhibitorBiological Activity: Biological Activity of PHA-793887Description PHA-793887 is a novel and potent inhibitor of CDK2, CDK5 and CDK7 with IC50 values of 8 nM, 5 nM…