Product Name: HMN-214Subtitle: Plk inhibitor,broad-spectrum anti-tumor agentBiological Activity: Biological Activity of HMN-214Description HMN-214, a prodrug of HMN-176, ispotent and broad-spectrumanti-tumor reagent. Targets PLK1 IC50SMLES: CC(=O)N(C1=CC=CC=C1C=CC2=CC=(C=C2))S(=O)(=O)C3=CC=C(C=C3)OCCAS NO: 1025720-94-8Standard In CHIKey: FXR…
Product Name: Ispinesib (SB-715992)Subtitle: Kinesin spindle protein (KSP)inhibitorBiological Activity: Biological Activity of Ispinesib (SB-715992)High affinity allosteric kinesin spindle protein (KSP) inhibitor (Ki app = 1.7 nM). Exhibits >10,000-fold selectivity for…
Product Name: SU 9516Subtitle: Cdk2 inhibitorBiological Activity: Biological Activity of SU 9516Potent, selective cdk2 inhibitor (IC50 values are 0.022, 0.04, 0.2, >10, >10, 18 and >100 μM for cdk2, cdk1,…
Product Name: ARRY 520 trifluoroacetateSubtitle: KSP inhibitorBiological Activity: Biological Activity of ARRY 520 trifluoroacetatePotent kinesin spindle protein (KSP) inhibitor (IC50 = 6 nM); selective for KSP over >250 other receptors…
Product Name: Aurora A Inhibitor ISubtitle: Aurora A inhibitorBiological Activity: Biological Activity of Aurora A Inhibitor IPotent and selective inhibitor of Aurora kinase A (IC50 = 3.4 nM); exhibits 1000-fold…
Product Name: BI 2536Subtitle: Plk1 inhibitor,potent and ATP-competitiveBiological Activity: Biological Activity of BI 2536Description BI2536 is a potent inhibitor of Plk1 with IC50 of 0.83 nM. Targets Plk1 IC50 0.83…
Product Name: Y-33075Subtitle: Biological Activity: SMLES: CC(C1=CC=C(C=C1)C(=O)NC2=C3C=CNC3=NC=C2)NCAS NO: 144875-48-9Standard In CHIKey: Elastase inhibitorsStandard InChI: Typrof Compound: Appearance: Formula: C16H16N4OM.Wt: 280.33General Tips: For obtaining a higher solubility , please warm the…
Product Name: VO-Ohpic trihydrateSubtitle: PTEN inhibitorBiological Activity: SMLES: CC((/N=C(O)/C/N=C(O)/(/N=C(O)/(N)()C(C)C)()CCCCN)()/C(O)=N/(/C(O)=N/(C(O)=N)()CO)()CC(C)C)()CCAS NO: 161715-21-5Standard In CHIKey: E1_E2_E3 Enzyme inhibitorsStandard InChI: Typrof Compound: Appearance: Formula: C12H15N2O11V+M.Wt: 414.2General Tips: For obtaining a higher solubility ,…
Product Name: Vc-MMADSubtitle: Potent tubulin inhibitorBiological Activity: SMLES: C1=CC=C2C(=C1)C(=NN=C2NC3=CC=C(C=C3)Cl)CC4=CC=NC=C4CAS NO: 1127498-03-6Standard In CHIKey: Dopamine beta)-hydroxylase inhibitorsStandard InChI: Typrof Compound: Appearance: Formula: C70H104N12O14SM.Wt: 1369.71General Tips: For obtaining a higher solubility ,…
Product Name: SCH900776 S-isomerSubtitle: Checkpoint kinase(Chk)inhibitorBiological Activity: SMLES: CN1C=C(C=N1)C2=C3N=C(C(=C(N3N=C2)N)Br)C4CCCNC4CAS NO: 1800401-93-7Standard In CHIKey: Dipeptidyl Peptidase inhibitorsStandard InChI: Typrof Compound: Appearance: Formula: C15H18BrN7M.Wt: 376.25General Tips: For obtaining a higher solubility ,…