Product Name: H-1152 dihydrochlorideSubtitle: Rho-kinase inhibitorBiological Activity: Biological Activity of H-1152 dihydrochlorideRho-kinase (ROCK) inhibitor that displays high selectivity over other protein kinases (IC50 values are 0.012, 0.180, 0.360, 0.745, 3.03,…
Product Name: H-1152Subtitle: Rho-kinase inhibitorBiological Activity: SMLES: CC1CNCCCN1S(=O)(=O)C2=CC=CC3=CN=CC(=C32)C.Cl.ClCAS NO: 1133432-49-1Standard In CHIKey: Aldehyde Dehydrogenase ALDH) inhibitorsStandard InChI: Typrof Compound: Appearance: Formula: C16H21N3O2SM.Wt: 319.42General Tips: For obtaining a higher solubility ,…
Product Name: GW843682XSubtitle: PLK1/PLK3 inhibitor,potent and selectiveBiological Activity: Biological Activity of GW843682XSelective inhibitor of polo-like kinase 1 (PLK1) and polo-like kinase 3 (PLK3) (IC50 values are 2.2 and 9.1 nM…
Product Name: GSK-923295Subtitle: CENP-E inhibitor,small-moleculeBiological Activity: Biological Activity of GSK-923295Description GSK-923295 is a small-molecule inhibitor of the mitotic kinesin centromere-associated protein E (CENP-E) with Ki value of 3.2 nM. Targets…
Product Name: GSK2606414Subtitle: PERK inhibitor,potent and selectiveBiological Activity: Biological Activity of GSK2606414Potent and selective protein kinase R-like ER kinase (PERK) inhibitor (IC50 = 0.4 nM). Exhibits >1000-fold selectivity for PERK…
Product Name: FlavopiridolSubtitle: Pan-cdk inhibitorBiological Activity: SMLES: CN1CC((C1)O)c2c(cc(c3c2oc(cc3=O)c4ccccc4Cl)O)OCAS NO: 872511-34-7Standard In CHIKey: BIIVYFLTOXDAOV-PXAZEXFGSA-N5 alpha Reductase inhibitorsStandard InChI: InChI=1S/C21H20ClNO5/c1-23-7-6-12(17(27)10-23)19-14(24)8-15(25)20-16(26)9-18(28-21(19)20)11-4-2-3-5-13(11)22/h2-5,8-9,12,17,24-25,27H,6-7,10H2,1H3/t12-,17+/m1/s1Typrof Compound: Appearance: Formula: C21H20ClNO5M.Wt: 401.85General Tips: For obtaining a higher solubility ,…
Product Name: Docetaxel TrihydrateSubtitle: Depolymerisation of microtubules inhibitorBiological Activity: SMLES: CC1=C2C(C(=O)C3(C(CC4C(C3C(C(C2(C)C)(CC1OC(=O)C(C(C5=CC=CC=C5)NC(=O)OC(C)(C)C)O)O)OC(=O)C6=CC=CC=C6)(CO4)OC(=O)C)O)C)O.O.O.OCAS NO: 1095173-27-5Standard In CHIKey: XCDIRYDKECHIPE-QHEQPUDQSA-N15-PGDH inhibitorsStandard InChI: InChI=1S/C43H53NO14.3H2O/c1-22-26(55-37(51)32(48)30(24-15-11-9-12-16-24)44-38(52)58-39(3,4)5)20-43(53)35(56-36(50)25-17-13-10-14-18-25)33-41(8,34(49)31(47)29(22)40(43,6)7)27(46)19-28-42(33,21-54-28)57-23(2)45;;;/h9-18,26-28,30-33,35,46-48,53H,19-21H2,1-8HTyprof Compound: Appearance: Formula: C43H59NO17M.Wt: 861.93General Tips: For obtaining a higher solubility…
Product Name: D-64131Subtitle: Tubulin polymerization inhibitorBiological Activity: Biological Activity of D-64131Novel inhibitor of tubulin polymerization; cytotoxic and inhibits tumor cell proliferation in vitro (IC50 = 74 nM). Prevents growth of…
Product Name: CVT-313Subtitle: Cdk2 inhibitorBiological Activity: SMLES: CC(C)N1C=NC2=C1N=C(N=C2NCC3=CC=C(C=C3)OC)N(CCO)CCOCAS NO: 25316-40-9Standard In CHIKey: VDAC inhibitorsStandard InChI: Typrof Compound: Appearance: Formula: C20H28N6O3M.Wt: 400.47General Tips: For obtaining a higher solubility , please warm…
Product Name: CHR-6494Subtitle: Haspin inhibitor,potent ands selectiveBiological Activity: SMLES: CCCNC1=NN2C(=NC=C2C3=CC4=C(C=C3)NN=C4)C=C1CAS NO: 120964-45-6Standard In CHIKey: URAT1 inhibitorsStandard InChI: Typrof Compound: Appearance: Formula: C16H16N6M.Wt: 292.34General Tips: For obtaining a higher solubility ,…