Product Name: 360A iodideSubtitle: G-quadruplex structures inhibitorBiological Activity: SMLES: CAS NO: 849217-68-1Standard In CHIKey: Naaddition)_HCO3- Cotransporter inhibitorsStandard InChI: Typrof Compound: Appearance: Formula: C27H23I2N5O2M.Wt: 703.31General Tips: For obtaining a higher solubility…
Product Name: 360ASubtitle: G-quadruplex structures inhibitorBiological Activity: SMLES: CAS NO: 1346242-81-6Standard In CHIKey: Naaddition)_Ca2addition) Exchanger inhibitorsStandard InChI: Typrof Compound: Appearance: Formula: C27H23N5O2+2M.Wt: 449.5General Tips: For obtaining a higher solubility ,…
Product Name: VE-821Subtitle: ATR kinase inhibitorBiological Activity: Biological Activity of VE-821Description VE-821 is a potent and selective ATP competitive inhibitor of ATR with Ki/IC50 of 13 nM/26 nM. Targets ATR…
Product Name: Nu 6027Subtitle: ATR/CDK inhibitor, potent and selectiveBiological Activity: Biological Activity of Nu 6027Description Nu 6027 is a selective inhibitor of CDK1 and CDK2 with IC50 value of 2.9…
Product Name: SNS-032 (BMS-387032)Subtitle: CDK inhibitorBiological Activity: Biological Activity of SNS-032 (BMS-387032)Potent inhibitor of cyclin-dependent kinases (cdks) 9, 2 and 7 (IC50 values are 4, 38 and 62 nM respectively).…
Product Name: NSC 23766Subtitle: Selective inhibitor of Rac1-GEF interaction.Biological Activity: Biological Activity of NSC 23766Selective inhibitor of Rac1-GEF interaction. Prevents Rac1 activation by Rac-specific guanine nucleotide exchange factors (GEFs) TrioN…
Product Name: LY2835219Subtitle: CDK4/6 inhibitor,potent and selectiveBiological Activity: Biological Activity of LY2835219Description LY2835219 is a potent and selective inhibitor of CDK4 and CDK6 with IC50 value of 2 nM and…
Product Name: Roscovitine (Seliciclib,CYC202)Subtitle: CDK inhibitor,potent and selectiveBiological Activity: Biological Activity of Roscovitine (Seliciclib,CYC202)Potent, selective inhibitor of cyclin-dependent kinases (cdk). Inhibits cdc2/cyclin B (IC50 = 650 nM), cdk2/cyclin A (IC50…
Product Name: Epothilone B (EPO906, Patupilone)Subtitle: Microtubule stabilizing macrolideBiological Activity: Biological Activity of Epothilone B (EPO906, Patupilone)Microtubule stabilization agent that promotes tubulin polymerization and induces G2-M cell cycle arrest (EC50…
Product Name: Epothilone ASubtitle: Microtubule stabilizing macrolideBiological Activity: Biological Activity of Epothilone ADescription Epothilone A is a macrolide antitumor agent with microtubule-stabilizing activity. Targets MDR CCRF-CEM/VBL100 cells IC50 20 nMSMLES:…