Product Name: D-64131
Subtitle: Tubulin polymerization inhibitor
Biological Activity: Biological Activity of D-64131Novel inhibitor of tubulin polymerization; cytotoxic and inhibits tumor cell proliferation in vitro (IC50 = 74 nM). Prevents growth of tumor models in mice following oral administration in vivo.
SMLES: COC1=CC2=C(C=C1)NC(=C2)C(=O)C3=CC=CC=C3
CAS NO: 571190-30-2
Standard In CHIKey: Metabolic Enzyme_Protease inhibitors
Standard InChI:
Typrof Compound:
Appearance:
Formula: C16H13NO2
M.Wt: 251.28
General Tips: For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.PubMed ID:http://jpet.aspetjournals.org/content/251/3/969
Shipping Condition: Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other courier with RT , or blue ice upon request.
Solubility: Soluble to 20 mM in ethanol and to 100 mM in DMSO
Storage: Store at RT
Purity: >98%
Chemical Name: (5-Methoxy-1H-indol-2-yl)phenylmethanone