Product Name: PD 0332991 (Palbociclib) HCl
Subtitle: CDK4/6 inhibitor,highly selective
Biological Activity: Biological Activity of PD 0332991 (Palbociclib) HClDescription Palbociclib (PD-0332991) HCl is a highly selective inhibitor of CDK4/6 with IC50 of 11 nM/16 nM. Targets CDK4/cyclin D1 CDK6/cyclin D2 IC50 11 nM 16 nM
SMLES: O=C1N(C2=NC(NC3=NC=C(C=C3)N4CCNCC4)=NC=C2C(C)=C1C(C)=O)C5CCCC5.Cl
CAS NO: 779353-01-4
Standard In CHIKey: HIV Protease inhibitors
Standard InChI:
Typrof Compound:
Appearance:
Formula: C24H30ClN7O2
M.Wt: 483.99
General Tips: For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.PubMed ID:http://jpet.aspetjournals.org/content/252/1/286
Shipping Condition: Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other courier with RT , or blue ice upon request.
Solubility: Limited solubility
Storage:
Purity: >98%
Chemical Name: 6-acetyl-8-cyclopentyl-5-methyl-2-((5-(piperazin-1-yl)pyridin-2-yl)amino)pyrido[2,3-d]pyrimidin-7(8H)-one hydrochloride