Product Name: AZ3146
Subtitle: Mps1 inhibitor,potent and selective
Biological Activity: Biological Activity of AZ3146Potent and selective monopolar spindle 1 (Mps1) kinase inhibitor (IC50 = 35 nM). Displays selectivity over 46 other kinases including Cdk1 and aurora kinase B. Interferes with chromosome alignment and overrides spindle assembl
SMLES:
CAS NO: 1629267-75-9
Standard In CHIKey: Isocitrate Dehydrogenase IDH) inhibitors
Standard InChI:
Typrof Compound:
Appearance:
Formula: C24H32N6O3
M.Wt: 452.55
General Tips: For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.PubMed ID:http://jpet.aspetjournals.org/content/252/1/312
Shipping Condition: Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other courier with RT , or blue ice upon request.
Solubility: Soluble to 25 mM in DMSO and to 75 mM in ethanol
Storage: Store at +4℃
Purity: >98%
Chemical Name: 9-Cyclopentyl-2-[[2-methoxy-4-[(1-methylpiperidin-4-yl)oxy]-phenyl]amino]-7-methyl-7,9-dihydro-8H-purin-8-one