Product Name: Topotecan hydrochloride
Subtitle: Topoisomerase 1 inhibitor
Biological Activity: Biological Activity of Topotecan hydrochloride 1. Topotecan hydrochloride, a topoisomerase I inhibitor, capable of inhibiting tumoral growth in animal models of retinoblastoma. 2. Topotecan hydrochloride liposomes loaded CS/β-GP hydrogel could become a p
SMLES: [Cl-].CC[C@@]1(O)C(=O)OCC2=C1C=C3N(Cc4cc5c(CN(C)C)c(O)ccc5nc34)C2=O.[H+]
CAS NO: 871362-31-1
Standard In CHIKey: DGHHQBMTXTWTJV-BQAIUKQQSA-NPI3K_Akt_mTOR inhibitors
Standard InChI: InChI=1S/C23H23N3O5.ClH/c1-4-23(30)16-8-18-20-12(9-26(18)21(28)15(16)11-31-22(23)29)7-13-14(10-25(2)3)19(27)6-5-17(13)24-20;/h5-8,27,30H,4,9-11H2,1-3H3;1H/t23-;/m0./s1
Typrof Compound: Alkaloids
Appearance: Powder
Formula: C23H24ClN3O5
M.Wt: 457.9
General Tips: For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.PubMed ID:http://jpet.aspetjournals.org/content/252/2/507
Shipping Condition: Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other courier with RT , or blue ice upon request.
Solubility: Soluble in DMSO > 10 mM
Storage:
Purity: ≥98%
Chemical Name: (S)-10-((dimethylamino)methyl)-4-ethyl-4,9-dihydroxy-1H-pyrano[3,4:6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione hydrochloride