Product Name: TH-302
Subtitle: Hypoxia-activated prodrug,inhibits H460/HT29 cell growth
Biological Activity: Biological Activity of TH-302Description TH-302 is a hypoxia-activated prodrug of the cytotoxin bromo-isophosphoramide mustard (Br-IPM). Targets thioredoxin reductase glutathione reductase IC50
SMLES: CN1C(=CN=C1[N+](=O)[O-])COP(=O)(NCCBr)NCCBr
CAS NO: 473727-83-2
Standard In CHIKey: Hippo MST) inhibitors
Standard InChI:
Typrof Compound:
Appearance:
Formula: C9H16Br2N5O4P
M.Wt: 449.04
General Tips: For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.PubMed ID:http://jpet.aspetjournals.org/content/252/2/778
Shipping Condition: Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other courier with RT , or blue ice upon request.
Solubility: Soluble in DMSO
Storage:
Purity: >98%
Chemical Name: 2-bromo-N-[(2-bromoethylamino)-[(3-methyl-2-nitroimidazol-4-yl)methoxy]phosphoryl]ethanamine