Product Name: ITF2357 (Givinostat)
Subtitle: HDAC inhibitor
Biological Activity: Biological Activity of ITF2357 (Givinostat)Description Givinostat (ITF2357) is a potent inhibitor of HDAC for maize HD2, HD1B and HD1A with IC50 of 10 nM, 7.5 nM and 16 nM, respectively. Targets HDAC IC50 7.5 to 16 nM
SMLES: CCN(CC)CC1=CC2=C(C=C(COC(NC3=CC=C(C(NO)=O)C=C3)=O)C=C2)C=C1.O.Cl
CAS NO: 83280-65-3
Standard In CHIKey: Vitamin D Related inhibitors
Standard InChI:
Typrof Compound:
Appearance:
Formula: C24H27N3O4.HCl.H2O
M.Wt: 475.97
General Tips: for obtaining a higher concentration: Please warm the tube at 37 °C for 10 minutes and/or shake it in the ultrasonic bath for a while.Stock solution can be stored below -20°C for several months.PubMed ID:http://jpet.aspetjournals.org/content/252/2/859
Shipping Condition: Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other courier with RT , or blue ice upon request.
Solubility: Soluble in DMSO > 10 mM
Storage:
Purity: >98%
Chemical Name: (6-((diethylamino)methyl)naphthalen-2-yl)methyl (4-(hydroxycarbamoyl)phenyl)carbamate hydrochloride hydrate