Product Name: Losartan Potassium (DuP 753)
Subtitle: Angiotensin AT1 receptor antagonist
Biological Activity: Biological Activity of Losartan Potassium (DuP 753)Selective non-peptide angiotensin AT1 receptor antagonist. Inhibits the contractile effects of angiotensin II on rabbit aorta and jugular vein (pA2 = 8.27). Orally active antihypertensive agent.
SMLES: CCCCC1=NC(=C(N1CC2=CC=C(C=C2)C3=CC=CC=C3C4=NN=N[N-]4)CO)Cl.[K+]
CAS NO: 404950-80-7
Standard In CHIKey: OXCMYAYHXIHQOA-UHFFFAOYSA-NAcids and Aldehydes inhibitors
Standard InChI: InChI=1S/C22H22ClN6O.K/c1-2-3-8-20-24-21(23)19(14-30)29(20)13-15-9-11-16(12-10-15)17-6-4-5-7-18(17)22-25-27-28-26-22;/h4-7,9-12,30H,2-3,8,13-14H2,1H3;/q-1;+1
Typrof Compound:
Appearance:
Formula: C22H23ClKN6O
M.Wt: 462.01
General Tips: For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.PubMed ID:http://jpet.aspetjournals.org/content/252/3/895
Shipping Condition: Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other courier with RT , or blue ice upon request.
Solubility: Soluble to 100 mM in water and to 100 mM in DMSO
Storage: Desiccate at RT
Purity: >98%
Chemical Name: 2-Butyl-4-chloro-1-[[2-(1H-tetrazol-5-yl)-[1,1-biphenyl]-4-yl]methyl]-1H-imidazole-5-methanol potassium salt