Product Name: TOK-001
Subtitle: CYP17 inhibitor and androgen receptor (AR) antagonist
Biological Activity: Biological Activity of TOK-001Description Galeterone(TOK-001) is a selective inhibitor of CYP17 and antagonist of androgen receptor (AR) with IC50 value of 300 nM and 384 nM, respectively Targets CYP17 Androgen Receptor IC50 300 nM
SMLES: CC12CCC(CC1=CCC3C2CCC4(C3CC=C4N5C=NC6=CC=CC=C65)C)O
CAS NO: 500579-04-4
Standard In CHIKey: ATM_ATR inhibitors
Standard InChI:
Typrof Compound:
Appearance:
Formula: C26H32N2O
M.Wt: 388.56
General Tips: For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.PubMed ID:http://jpet.aspetjournals.org/content/253/1/266
Shipping Condition: Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other courier with RT , or blue ice upon request.
Solubility: Soluble in DMSO > 10 mM
Storage:
Purity: >98%
Chemical Name: (3S,8R,9S,10R,13S,14S)-17-(benzimidazol-1-yl)-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15-decahydro-1H-cyclopenta[a]phenanthren-3-ol