Product Name: CX-6258
Subtitle: Pan-Pim kinases Inhibitor
Biological Activity: Biological Activity of CX-6258Description CX-6258 HCl is a potent, orally efficacious inhibitor of pan-Pim kinase with IC50 of 5 nM, 25 nM and 16 nM for Pim1, Pim2, and Pim3, respectively. Targets Pim1 Pim3 Pim2 IC50 5 nM 16 nM 25 n
SMLES: CN1CCCN(C(C2=CC(C3=CC=C(/C=C4C(C=C(Cl)C=C5)=C5NC4=O)O3)=CC=C2)=O)CC1
CAS NO: 1247825-37-1
Standard In CHIKey: CaSR inhibitors
Standard InChI:
Typrof Compound:
Appearance:
Formula: C26H24ClN3O3
M.Wt: 461.94
General Tips: For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.PubMed ID:http://jpet.aspetjournals.org/content/253/2/594
Shipping Condition: Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other courier with RT , or blue ice upon request.
Solubility: Soluble in DMSO > 10 mM
Storage:
Purity: >98%
Chemical Name: (E)-5-chloro-3-((5-(3-(4-methyl-1,4-diazepane-1-carbonyl)phenyl)furan-2-yl)methylene)indolin-2-one