Product Name: NVP-BSK805
Subtitle: ATP-competitive JAK2 inhibitor
Biological Activity: Biological Activity of NVP-BSK805Description NVP-BSK805 is a potent and selective ATP-competitive inhibitor of JAK2 with IC50 of 0.5 nM,>20-fold selectivity towards JAK1, JAK3 and TYK2. Targets JAK2 IC50 0.5 nM
SMLES: C1CNCCC1N2C=C(C=N2)C3=NC4=C(C=CC=C4N=C3)C5=CC(=C(C(=C5)F)CN6CCOCC6)F.Cl.Cl
CAS NO: 1374639-75-4
Standard In CHIKey: Endothelin Receptor inhibitors
Standard InChI:
Typrof Compound:
Appearance:
Formula: C27H28F2N6O
M.Wt: 490.55
General Tips: For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.PubMed ID:http://jpet.aspetjournals.org/content/253/2/655
Shipping Condition: Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other courier with RT , or blue ice upon request.
Solubility: Soluble in DMSO
Storage:
Purity: >98%
Chemical Name: 4-[[2,6-difluoro-4-[3-(1-piperidin-4-ylpyrazol-4-yl)quinoxalin-5-yl]phenyl]methyl]morpholine;dihydrochloride