Product Name: OTX-015
Subtitle: BRD inhibitor
Biological Activity: Biological Activity of OTX-015Description OTX-015 is an orally bioavailable and small molecule inhibitor of bromodomain and extra terminal domain (BET) family proteins with EC50 values of 10-19 nM for BRD2, BRD3, and BRD4. Targets BRD2 BRD3 BRD4
SMLES: Clc1ccc(cc1)/C4=N/[C@H](c2nnc(n2c3sc(c(c34)C)C)C)CC(=O)Nc5ccc(O)cc5
CAS NO: 828934-41-4
Standard In CHIKey: GHSR inhibitors
Standard InChI:
Typrof Compound:
Appearance:
Formula: C25H22ClN5O2S
M.Wt: 491.99
General Tips: for obtaining a higher concentration: Please warm the tube at 37℃ for 10 minutes and/or shake it in the ultrasonic bath for a while. Stock solution can be stored below -20℃ for several months.PubMed ID:http://jpet.aspetjournals.org/content/253/2/661
Shipping Condition: Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other courier with RT , or blue ice upon request.
Solubility: Soluble in DMSO > 10 mM
Storage:
Purity: >98%
Chemical Name: birabresib