Product Name: JNJ-7706621
Subtitle: Potent CDK/Aurora kinase inhibitor
Biological Activity: Biological Activity of JNJ-7706621Description JNJ-7706621 is a potent inhibitor of cyclin-dependent kinases (CDK) and Aurora kinases with IC50 values of 9 nM, 4 nM, 11 nM and 15 nM for CDK1, 2 and Aurora A, B, respectively. Targets CDK1 CDK2 Auro
SMLES: C1=CC(=C(C(=C1)F)C(=O)N2C(=NC(=N2)NC3=CC=C(C=C3)S(=O)(=O)N)N)F
CAS NO: 121032-29-9
Standard In CHIKey: Motilin Receptor inhibitors
Standard InChI:
Typrof Compound:
Appearance:
Formula: C15H12F2N6O3S
M.Wt: 394.36
General Tips: For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.PubMed ID:http://jpet.aspetjournals.org/content/253/2/812
Shipping Condition: Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other courier with RT , or blue ice upon request.
Solubility: Soluble in DMSO > 10 mM
Storage:
Purity: >98%
Chemical Name: 4-[[5-amino-1-(2,6-difluorobenzoyl)-1,2,4-triazol-3-yl]amino]benzenesulfonamide