Product Name: LY2784544
Subtitle: JAK2 inhibitor,highly potent and selective
Biological Activity: Biological Activity of LY2784544Description LY2784544 is a highly potent and selective inhibitor of wild-type JAK2 and V617F mutant JAK2 with IC50 values of 2.26 μM and 55 nM, respectively. Targets wild-type JAK2 V617F mutant JAK2 IC5
SMLES: CC1=CC(=NN1)NC2=NN3C(=C(N=C3C(=C2)CN4CCOCC4)C)CC5=C(C=C(C=C5)Cl)F
CAS NO: 1005491-05-3
Standard In CHIKey: NO Synthase inhibitors
Standard InChI:
Typrof Compound:
Appearance:
Formula: C23H25ClFN7O
M.Wt: 469.94
General Tips: For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.PubMed ID:http://jpet.aspetjournals.org/content/253/3/1083
Shipping Condition: Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other courier with RT , or blue ice upon request.
Solubility: Soluble in DMSO > 10 mM
Storage:
Purity: >98%
Chemical Name: 3-[(4-chloro-2-fluorophenyl)methyl]-2-methyl-N-(5-methyl-1H-pyrazol-3-yl)-8-(morpholin-4-ylmethyl)imidazo[1,2-b]pyridazin-6-amine