Product Name: SGC 0946
Subtitle: DOT1L inhibitor,highly potent and selective
Biological Activity: Biological Activity of SGC 0946Description SGC 0946 is a potent inhibitor of DOT1L methyltransferase with IC50 value of 0.3 nM. Targets DOT1L IC50 0.3 nM
SMLES: CC(C)(C)C1=CC=C(NC(NCCCN(C[C@@H]2[C@@H](O)[C@@H](O)[C@H](N3C4=NC=NC(N)=C4C(Br)=C3)O2)C(C)C)=O)C=C1
CAS NO: 405911-17-3
Standard In CHIKey: STAT inhibitors
Standard InChI:
Typrof Compound:
Appearance:
Formula: C28H40BrN7O4
M.Wt: 618.57
General Tips: For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.PubMed ID:http://jpet.aspetjournals.org/content/253/3/1162
Shipping Condition: Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other courier with RT , or blue ice upon request.
Solubility: Soluble in DMSO > 10 mM
Storage:
Purity: >98%
Chemical Name: N-(9,10-dioxo-9,10-dihydrophenanthren-2-yl)pivalamide