Product Name: EX 527 (SEN0014196)
Subtitle: SIRT1 inhibitor
Biological Activity: Biological Activity of EX 527 (SEN0014196)Selective inhibitor of SIRT1 that does not inhibit histone deacetylase (HDAC) or other sirtuin deacetylase family members (IC50 values are 98, 19600, 48700, > 100000 and > 100000 nM for SIRT1, SIRT2, SIRT3,
SMLES: C1CC(C2=C(C1)C3=C(N2)C=CC(=C3)Cl)C(=O)N
CAS NO: 690270-29-2
Standard In CHIKey: Mixed Lineage Kinase inhibitors
Standard InChI:
Typrof Compound:
Appearance:
Formula: C13H13ClN2O
M.Wt: 248.71
General Tips: For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.PubMed ID:http://jpet.aspetjournals.org/content/253/3/1206
Shipping Condition: Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other courier with RT , or blue ice upon request.
Solubility: Soluble to 75 mM in DMSO and to 50 mM in ethanol
Storage: Store at +4℃
Purity: >98%
Chemical Name: 6-Chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide