Product Name: TC-A 2317 hydrochloride
Subtitle: Aurora kinase A inhibitor,potent and selective
Biological Activity: Biological Activity of TC-A 2317 hydrochloridePotent Aurora kinase A inhibitor (Ki = 1.2 nM compared to 101 nM for inhibition of Aurora kinase B). Selective over 60 other kinases (IC50 values > 1000 nM). Exhibits good cell permeability and antitumor a
SMLES: CC(CCCC(C)(C)O)NC1=NC(NC2=NNC(C)=C2)=CC(C)=C1[N+]#[C-].Cl
CAS NO: 1808011-22-4
Standard In CHIKey: CFTR inhibitors
Standard InChI:
Typrof Compound:
Appearance:
Formula: C19H28N6O.HCl
M.Wt: 392.93
General Tips: For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.PubMed ID:http://jpet.aspetjournals.org/content/253/3/1259
Shipping Condition: Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other courier with RT , or blue ice upon request.
Solubility: Soluble to 100 mM in DMSO and to 50 mM in ethanol
Storage: Store at +4℃
Purity: >98%
Chemical Name: 2-[(5-Hydroxy-1,5-dimethylhexyl)amino]-4-methyl-6-[(5-methyl-1H-pyrazol-3-yl)amino]-3-pyridinecarbonitrile hydrochloride