Product Name: DMOG
Subtitle: Competitive HIF-PH inhibitor, cell-permeable
Biological Activity: Biological Activity of DMOGProlyl 4-hydroxylase (P4H) inhibitor; inhibits hypoxia-inducible factor α (HIF-α) prolyl hydroxylase (HIF-PH). Increases levels of HIF-1α; promotes cell survival under hypoxic conditions.
SMLES: COC(=O)CNC(=O)C(=O)OC
CAS NO: 191732-72-6
Standard In CHIKey: BNJOZDZCRHCODO-UHFFFAOYSA-NGlyT inhibitors
Standard InChI: InChI=1S/C6H9NO5/c1-11-4(8)3-7-5(9)6(10)12-2/h3H2,1-2H3,(H,7,9)
Typrof Compound:
Appearance:
Formula: C6H9NO5
M.Wt: 175.14
General Tips: For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.PubMed ID:http://jpet.aspetjournals.org/content/253/3/899
Shipping Condition: Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other courier with RT , or blue ice upon request.
Solubility: Soluble to 100 mM in water and to 100 mM in DMSO
Storage: Store at -20℃
Purity: >98%
Chemical Name: N-(2-Methoxy-2-oxoacetyl)glycine methyl ester