Product Name: GLPG0634
Subtitle: JAK1 inhibitor, potent and selective
Biological Activity: Biological Activity of GLPG0634Description GLPG0634 is a selective JAK1 inhibitor with IC50 of 10 nM, 28 nM, 810 nM, and 116 nM for JAK1, JAK2, JAK3, and TYK2, respectively. Targets JAK1 JAK2 TYK2 JAK3 IC50 10 nM 28 nM 116 nM 810 nM
SMLES: N/A
CAS NO: 603148-36-3
Standard In CHIKey: PI3K/Akt/mTOR_Compound_Library inhibitors
Standard InChI:
Typrof Compound:
Appearance:
Formula: C23H18N6O2
M.Wt: 410.43
General Tips: For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.PubMed ID:http://jpet.aspetjournals.org/content/255/1/114
Shipping Condition: Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other courier with RT , or blue ice upon request.
Solubility: Limited solubility
Storage:
Purity: >98%
Chemical Name: N-[5-[4-[(1,1-dioxo-1,4-thiazinan-4-yl)methyl]phenyl]-[1,2,4]triazolo[1,5-a]pyridin-2-yl]cyclopropanecarboxamide