Product Name: Pemetrexed disodium
Subtitle: TS, DHFR,GARFT and AICARFT inhibitor
Biological Activity: Biological Activity of Pemetrexed disodium 1. Pemetrexed disodium activates MEK/ERK-dependent cyto-protective autophagy, and inhibition of this pathway potentiates Pemetrexed disodiums activity in HepG2 cells. 2. Pemetrexed disodium is a multitargeted a
SMLES: [Na+].[Na+].NC1=NC(=O)c2c([nH]cc2CCc3ccc(cc3)C(=O)N[C@H](CCC([O-])=O)C([O-])=O)N1
CAS NO: 937263-43-9
Standard In CHIKey: NYDXNILOWQXUOF-FFXKMJQXSA-L5-HT Receptor inhibitors
Standard InChI: InChI=1S/C20H21N5O6.2Na/c21-20-24-16-15(18(29)25-20)12(9-22-16)6-3-10-1-4-11(5-2-10)17(28)23-13(19(30)31)7-8-14(26)27;;/h1-2,4-5,9,13H,3,6-8H2,(H,23,28)(H,26,27)(H,30,31)(H4,21,22,24,25,29);;/q;2*+1/p-2/t13-;;/m1../s1
Typrof Compound: Miscellaneous
Appearance: Powder
Formula: C20H19N5Na2O6
M.Wt: 471.37
General Tips: For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.PubMed ID:http://jpet.aspetjournals.org/content/255/2/795
Shipping Condition: Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other courier with RT , or blue ice upon request.
Solubility: Limited solubility
Storage:
Purity: ≥98%
Chemical Name: disodium;(2S)-2-[[4-[2-(2-amino-4-oxo-1,7-dihydropyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]amino]pentanedioate