Product Name: GDC-0349
Subtitle: MTOR inhibitor
Biological Activity: Biological Activity of GDC-0349Description GDC-0349 is a potent and selective ATP-competitive inhibitor of mTOR with Ki value of 3.8 nM. Targets mTOR IC50 3.8 nM (Ki)
SMLES: CCNC(=O)NC1=CC=C(C=C1)C2=NC3=C(CCN(C3)C4COC4)C(=N2)N5CCOCC5C
CAS NO: 606143-89-9
Standard In CHIKey: Fungal inhibitors
Standard InChI:
Typrof Compound:
Appearance:
Formula: C24H32N6O3
M.Wt: 452.55
General Tips: For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.PubMed ID:http://jpet.aspetjournals.org/content/257/1/374
Shipping Condition: Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other courier with RT , or blue ice upon request.
Solubility: Soluble in DMSO > 10 mM
Storage:
Purity: >98%
Chemical Name: 1-ethyl-3-[4-[4-[(3S)-3-methylmorpholin-4-yl]-7-(oxetan-3-yl)-6,8-dihydro-5H-pyrido[3,4-d]pyrimidin-2-yl]phenyl]urea