Product Name: CHIR-98014
Subtitle: GSK-3β inhibitor,selective and ATP-competitive
Biological Activity: Biological Activity of CHIR-98014Description CHIR-98014 is a potent inhibitor of GSK-3α and GSK-3β with IC50 values of 0.65 nM and 0.58 nM, respectively. Targets GSK-3β GSK-3α p70 S6K IC50 0.58 nM 0.65 nM >1 μM
SMLES: C1=CC(=C(C=C1Cl)Cl)C2=NC(=NC=C2N3C=CN=C3)NCCNC4=NC(=C(C=C4)[N+](=O)[O-])N
CAS NO: 1562338-42-4
Standard In CHIKey: Histone Demethylase inhibitors
Standard InChI:
Typrof Compound:
Appearance:
Formula: C20H17Cl2N9O2
M.Wt: 486.31
General Tips: For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.PubMed ID:http://jpet.aspetjournals.org/content/257/2/850
Shipping Condition: Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other courier with RT , or blue ice upon request.
Solubility: Limited solubility
Storage:
Purity: >98%
Chemical Name: 6-N-[2-[[4-(2,4-dichlorophenyl)-5-imidazol-1-ylpyrimidin-2-yl]amino]ethyl]-3-nitropyridine-2,6-diamine