Product Name: JK 184
Subtitle: Hh signaling inhibitor
Biological Activity: Biological Activity of JK 184Potent downstream hedgehog (Hh) signaling inhibitor that prevents Gli-dependent transcriptional activity (IC50 = 30 nM). Exhibits antiproliferative activity in a range of cancer cell lines (GI50 = 3 – 21 nM) and in human xenog
SMLES: CCOC1=CC=C(C=C1)NC2=NC(=CS2)C3=C(N=C4N3C=CC=C4)C
CAS NO: 79517-01-4
Standard In CHIKey: Xanthine Oxidase inhibitors
Standard InChI:
Typrof Compound:
Appearance:
Formula: C19H18N4OS
M.Wt: 350.44
General Tips: For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.PubMed ID:http://jpet.aspetjournals.org/content/259/2/884
Shipping Condition: Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other courier with RT , or blue ice upon request.
Solubility: Soluble to 100 mM in DMSO and to 25 mM in ethanol
Storage: Store at +4℃
Purity: >98%
Chemical Name: N-(4-Ethoxyphenyl)-4-(2-methylimidazo[1,2-a]pyridin-3-yl)-2-thiazolamine