Product Name: EO 1428
Subtitle:
Biological Activity: Biological Activity of EO 1428Selective inhibitor of p38α and p38β2 that displays no activity at p38γ, p38δ, ERK1/2 and JNK1. Inhibits production of inflammatory cytokines including IL-8, TNF-α, IL-6, IL-1β and IL-10 (IC50 values a
SMLES: BrC1=CC=C(C(N)=C1)NC2=CC=C(C(Cl)=C2)C(C3=CC=CC=C3C)=O
CAS NO: 175026-96-7
Standard In CHIKey: Histone Demethylase inhibitors
Standard InChI:
Typrof Compound:
Appearance:
Formula: C20H16BrClN2O
M.Wt: 415.71
General Tips: For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.PubMed ID:http://jpet.aspetjournals.org/content/266/2/684
Shipping Condition: Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other courier with RT , or blue ice upon request.
Solubility: Soluble to 100 mM in DMSO and to 50 mM in ethanol
Storage: Store at +4℃
Purity: >98%
Chemical Name: (2-Methylphenyl)-[4-[(2-amino-4-bromophenyl)amino]-2-chlorophenyl]methanone