Product Name: SX 011
Subtitle:
Biological Activity: Biological Activity of SX 011Potent p38α inhibitor (IC50 = 9 nM). Also inhibits p38β and JNK-2 (IC50 values are 90 nM and 100 nM respectively). Displays no significant activity at p38γ, p38δ, ERK-2 and JNK-1.
SMLES: ClC1=C(C=C2C(N(C)C=C2C(C(N(C)C)=O)=O)=C1)C(N3CCC(CC(C=C4)=CC=C4F)CC3)=O
CAS NO: 16409
Standard In CHIKey: Adenylate Cyclase inhibitors
Standard InChI:
Typrof Compound:
Appearance:
Formula: C26H27ClFN3O3
M.Wt: 483.96
General Tips: For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.PubMed ID:http://jpet.aspetjournals.org/content/266/2/726
Shipping Condition: Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other courier with RT , or blue ice upon request.
Solubility: Soluble to 100 mM in DMSO and to 100 mM in ethanol
Storage: Store at RT
Purity: >98%
Chemical Name: 6-Chloro-5-[[4-[(4-fluorophenyl)methyl]-1-piperidinyl]carbonyl-N,N,1-trimethyl-α-oxo-1H-indole-3-acetamide