Product Name: Panobinostat (LBH589)Subtitle: HDAC inhibitorBiological Activity: Biological Activity of Panobinostat (LBH589)Description Panobinostat (LBH589) is a novel broad-spectrum inhibitor of HDAC with IC50 of 5 nM. Targets HDAC (MOLT-4 cells)…
Product Name: ApicidinSubtitle: Potent HDAC inhibitorBiological Activity: Biological Activity of ApicidinPotent histone deacetylase (HDAC) inhibitor (IC50 = 0.7 nM in an enzyme activity assay). Antiangiogenic and anti-invasive; blocks proliferation of…
Product Name: Romidepsin (FK228, depsipeptide)Subtitle: HDAC1/HDAC2 inhibitor,potent and selectiveBiological Activity: Biological Activity of Romidepsin (FK228, depsipeptide)Potent and selective inhibitor of class I histone deacetylases (HDACs) (IC50 values are 36, 47,…
Product Name: Entinostat (MS-275,SNDX-275)Subtitle: HDAC1 and HDAC3 inhibitorBiological Activity: Biological Activity of Entinostat (MS-275,SNDX-275)Description Entinostat (MS-275) is a strong inhibitor of HDAC1 and HDAC3 with IC50 of 0.51 μM and…
Product Name: OfloxacinSubtitle: Fluoroquinolones,antibioticsBiological Activity: SMLES: FC1=C(C2=C(C3=C1)N(C()=C(C(O)=O)C3=O)C(C()())()C()()O2)N4C()()C()()N(C()())C()()C4()CAS NO: 855527-92-3Standard In CHIKey: GSDSWSVVBLHKDQ-UHFFFAOYSA-NMAPK_Compound_Library inhibitorsStandard InChI: InChI=1S/C18H20FN3O4/c1-10-9-26-17-14-11(16(23)12(18(24)25)8-22(10)14)7-13(19)15(17)21-5-3-20(2)4-6-21/h7-8,10H,3-6,9H2,1-2H3,(H,24,25)Typrof Compound: Appearance: Formula: C18H20FN3O4M.Wt: 361.37General Tips: For obtaining a higher solubility , please warm the…
Product Name: FludarabineSubtitle: DNA synthsis inhibitorBiological Activity: Biological Activity of FludarabinePurine analog that inhibits DNA synthesis. Exhibits antiproliferative activity (IC50 = 1.54 μM in RPMI cells) and triggers apoptosis through…
Product Name: Moxifloxacin HClSubtitle: Fluoroquinolone antibioticBiological Activity: SMLES: COC1=C2C(=CC(=C1N3CC4CCCNC4C3)F)C(=O)C(=CN2C5CC5)C(=O)O.ClCAS NO: 1260251-31-7Standard In CHIKey: IDIIJJHBXUESQI-UHFFFAOYSA-NJAK/STAT_Compound_Library inhibitorsStandard InChI: InChI=1S/C21H24FN3O4.ClH/c1-29-20-17-13(19(26)14(21(27)28)9-25(17)12-4-5-12)7-15(22)18(20)24-8-11-3-2-6-23-16(11)10-24;/h7,9,11-12,16,23H,2-6,8,10H2,1H3,(H,27,28);1HTyprof Compound: Appearance: Formula: C21H24FN3O4.HClM.Wt: 437.89General Tips: For obtaining a higher solubility , please…
Product Name: IrinotecanSubtitle: Topoisomerase I inhibitorBiological Activity: SMLES: O=C(OC1)C(O)(CC)C2=C1C(N(CC3=C4N=C5C(C=C(OC(N6CCC(N7CCCCC7)CC6)=O)C=C5)=C3CC)C4=C2)=OCAS NO: 1621523-07-6Standard In CHIKey: UWKQSNNFCGGAFS-XIFFEERXSA-NImmunology/Inflammation_Compound_Library inhibitorsStandard InChI: InChI=1S/C33H38N4O6/c1-3-22-23-16-21(43-32(40)36-14-10-20(11-15-36)35-12-6-5-7-13-35)8-9-27(23)34-29-24(22)18-37-28(29)17-26-25(30(37)38)19-42-31(39)33(26,41)4-2/h8-9,16-17,20,41H,3-7,10-15,18-19H2,1-2H3/t33-/m0/s1Typrof Compound: Appearance: Formula: C33H38N4O6M.Wt: 586.68General Tips: For obtaining a higher solubility , please…
Product Name: KU 55933Subtitle: ATM inhibitor,potent and selectiveBiological Activity: Biological Activity of KU 55933Potent, selective and competitive ATM kinase inhibitor (Ki = 2.2 nM, IC50 values are 13, 2500, 9300,…
Product Name: TubacinSubtitle: HDAC6 inhibitor,potent,selective,reversible,cell-permeableBiological Activity: Biological Activity of TubacinDescription Tubacin is a highly potent and selective, reversible, cell-permeable inhibitor of HDAC6 with an IC50 value of 4 nM. Targets…