Product Name: Valproic acid sodium salt (Sodium valproate)Subtitle: HDAC inhibitorBiological Activity: Biological Activity of Valproic acid sodium salt (Sodium valproate)Histone deacetylase inhibitor (IC50 = 400 μM) that exhibits anticancer, anti-inflammatory…
Product Name: PCI-24781 (CRA-024781)Subtitle: Pan-HDAC inhibitorBiological Activity: Biological Activity of PCI-24781 (CRA-024781)Description PCI-24781 is an inhibitor of HDACs with Ki values of 7 nM, 8.2 nM, 17 nM and 19…
Product Name: Belinostat (PXD101)Subtitle: Hydroxamate-type HDAC inhibitorBiological Activity: Biological Activity of Belinostat (PXD101)Description Belinostat (PXD101) is a novel inhibitor of pan-HDAC with an IC50 value of 27 nM. Targets pan-HDAC…
Product Name: Pracinostat (SB939)Subtitle: Pan-HDAC inhibitorBiological Activity: Biological Activity of Pracinostat (SB939)Description Pracinostat (SB939) is a potent inhibitor of HDAC with IC50 of 40-140 nM with exception for HDAC6. Targets…
Product Name: MC1568Subtitle: Class II HDAC inhibitor,potent andBiological Activity: Biological Activity of MC1568Selective inhibitor of class IIa histone deacetylases (HDACs). Exhibits tissue-selective inhibition between members of class II deacetylases in…
Product Name: ITF2357 (Givinostat)Subtitle: HDAC inhibitorBiological Activity: Biological Activity of ITF2357 (Givinostat)Description Givinostat (ITF2357) is a potent inhibitor of HDAC for maize HD2, HD1B and HD1A with IC50 of 10…
Product Name: CUDC-101Subtitle: Multitargeted HDAC inhibitorBiological Activity: Biological Activity of CUDC-101Description CUDC-101 is a potent inhibitor of HDAC, EGFR and HER2 with IC50 values of 4.4 nM, 2.4 nM, and…
Product Name: PCI-34051Subtitle: HDAC8 inhibitor,potent and selectiveBiological Activity: Biological Activity of PCI-34051Potent and selective histone deacetylase 8 (HDAC8) inhibitor (IC50 = 10 nM). Displays >200 fold selectivity over HDAC isoforms…
Product Name: JNJ-26481585Subtitle: Potent HDAC inhibitorBiological Activity: Biological Activity of JNJ-26481585Description Quisinostat (JNJ-26481585) is a novel second-generation inhibitor of HDAC with highest potency for HDAC1 with IC50 of 0.11 nM.…
Product Name: Mocetinostat (MGCD0103, MG0103)Subtitle: HDAC inhibitor,isotype-selective and potentBiological Activity: Biological Activity of Mocetinostat (MGCD0103, MG0103)Description Mocetinostat (MGCD0103) is a potent inhibitor of HDAC with most potency for HDAC1 with…