Product Name: Zibotentan (ZD4054)Subtitle: ETA receptor antagonist,potent and specificBiological Activity: Biological Activity of Zibotentan (ZD4054)Description Zibotentan (ZD4054) is a specific antagonist of Endothelin (ET)A with an IC50 value of 21…
Product Name: TranilastSubtitle: Angiogenesis inhibitorBiological Activity: Biological Activity of TranilastAntiallergic via inhibition of chemical mediator release from mast cells. Shown to be an effective inhibitor of angiogenesis. Demonstrated to antagonize…
Product Name: Prazosin HClSubtitle: α1 and α2B-adrenoceptor antagonistBiological Activity: Biological Activity of Prazosin HClα1 and α2B-adrenoceptor antagonist. Also a potent antagonist at the melatonin MT3 receptor (Ki = 10.2 nM).…
Product Name: Alfuzosin HClSubtitle: α1 adrenoceptor antagonist,functionally uro-selectiveBiological Activity: Biological Activity of Alfuzosin HClFunctionally uro-selective α1 adrenoceptor antagonist that does not discriminate between α1 subtypes. Inhibits increases in intraurethral pressure…
Product Name: MethylprednisoloneSubtitle: Apoptosis inducer,GR agonistBiological Activity: Biological Activity of MethylprednisoloneGlucocorticoid receptor (GR) agonist. Displays anti-inflammatory and antioxidant properties. Attenuates apoptosis in oligodendrocytes after injury stimuli. Upregulates expression of Bcl-xL…
Product Name: VerlukastSubtitle: Biological Activity: SMLES: CN(C)C(=O)CCSC(C1=CC=CC(=C1)C=CC2=NC3=C(C=CC(=C3)Cl)C=C2)SCCC(=O)OCAS NO: 17318-31-9Standard In CHIKey: AXUZQJFHDNNPFG-UXBLZVDNSA-NApoptosis inhibitorsStandard InChI: InChI=1S/C26H27ClN2O3S2/c1-29(2)24(30)12-14-33-26(34-15-13-25(31)32)20-5-3-4-18(16-20)6-10-22-11-8-19-7-9-21(27)17-23(19)28-22/h3-11,16-17,26H,12-15H2,1-2H3,(H,31,32)/b10-6+Typrof Compound: Appearance: Formula: C26H27ClN2O3S2M.Wt: 515.09General Tips: For obtaining a higher solubility , please warm the…
Product Name: TUG-770Subtitle: FFA1/GPR40 agonistBiological Activity: SMLES: C1=CC=C(C(=C1)CC#N)C#CC2=CC(=C(C=C2)CCC(=O)O)FCAS NO: 1628208-23-0Standard In CHIKey: Drug-Linker Conjugates for ADC inhibitorsStandard InChI: Typrof Compound: Appearance: Formula: C19H14FNO2M.Wt: 307.32General Tips: For obtaining a higher solubility…
Product Name: TozadenantSubtitle: Adenosine 2a receptor antagonist,novel and selectiveBiological Activity: Biological Activity of TozadenantDescription Tozadenant is an antagonist of adenosine A2A receptor. Targets adenosine A2A receptor IC50SMLES: CC1(CCN(CC1)C(=O)NC2=NC3=C(C=CC(=C3S2)N4CCOCC4)OC)OCAS NO: 78186-34-2Standard…
Product Name: TaranabantSubtitle: Biological Activity: SMLES: CC(C(CC1=CC=C(C=C1)Cl)C2=CC=CC(=C2)C#N)NC(=O)C(C)(C)OC3=NC=C(C=C3)C(F)(F)FCAS NO: 1374516-07-0Standard In CHIKey: ADC Cytotoxin inhibitorsStandard InChI: Typrof Compound: Appearance: Formula: C27H25ClF3N3O2M.Wt: 515.97General Tips: For obtaining a higher solubility , please warm…
Product Name: Talnetant hydrochlorideSubtitle: NK3 receptor antagonistBiological Activity: SMLES: CCC(C1=CC=CC=C1)NC(=O)C2=C(C(=NC3=CC=CC=C32)C4=CC=CC=C4)O.ClCAS NO: 173865-33-3Standard In CHIKey: BHCSUEHQURQVLD-BDQAORGHSA-NAntibody-drug Conjugate_ADC Related inhibitorsStandard InChI: InChI=1S/C25H22N2O2.ClH/c1-2-20(17-11-5-3-6-12-17)27-25(29)22-19-15-9-10-16-21(19)26-23(24(22)28)18-13-7-4-8-14-18;/h3-16,20,28H,2H2,1H3,(H,27,29);1H/t20-;/m0./s1Typrof Compound: Appearance: Formula: C25H23ClN2O2M.Wt: 418.92General Tips: For obtaining a higher…