Product Name: YM 750Subtitle: Biological Activity: Biological Activity of YM 750Acyl-CoA:cholesterol acyltransferase (ACAT) inhibitor (IC50 = 0.18 μM). Exhibits hypocholesterolaemic and antiatherosclerotic activity in vivo.SMLES: O=C(NC1=C(C)C=C(C)C=C1C)N(CC2=CC=C3C(CC4=CC=CC=C34)=C2)C5CCCCCC5CAS NO: 1310726-60-3Standard In CHIKey:…
Product Name: VULM 1457Subtitle: Biological Activity: Biological Activity of VULM 1457Acyl-CoA: cholesterol acyltransferase (ACAT) inhibitor. Decreases cholesterol levels in the plasma and liver of diabetic-hypercholesterolemic rats.SMLES: O=C(NC(C=C1)=CC=C1SC(C=C2)=CC=C2()=O)NC(C(C(C)C)=CC=C3)=C3C(C)CCAS NO: 497223-25-3Standard In…
Product Name: TautomycetinSubtitle: Biological Activity: Biological Activity of TautomycetinSelective inhibitor of protein phosphatase (PP)1 (IC50 values are 1.6 and 62 nM for PP1 and PP2 respectively). Reduces PDGF-induced vascular smooth…
Product Name: CI 976Subtitle: Biological Activity: Biological Activity of CI 976Selective acyl-coenzyme A:cholesterol acyltransferase (ACAT) inhibitor (IC50 = 0.073 μM). Lowers non-high density lipoprotein (HDL)-cholesterol and increases HDL-cholesterol concentrations in…
Product Name: NSC 663284Subtitle: Biological Activity: Biological Activity of NSC 663284Potent, selective inhibitor of Cdc25 dual specificity phosphatases (Ki values are 29, 95 and 89 nM for human Cdc25A, Cdc25B2…
Product Name: NSC 95397Subtitle: Biological Activity: Biological Activity of NSC 95397Potent and selective irreversible inhibitor of Cdc25 dual specificity phosphatases (Ki values are 32, 96 and 40 nM for inhibition…
Product Name: SGC707Subtitle: PRMT3 inhibitorBiological Activity: SMLES: O=C(NCC(N1CCCC1)=O)NC2=CC3=CC=NC=C3C=C2CAS NO: 1262417-51-5Standard In CHIKey: Anti-infection inhibitorsStandard InChI: Typrof Compound: Appearance: Formula: C16H18N4O2M.Wt: 298.34General Tips: For obtaining a higher solubility , please warm…
Product Name: Peficitinb (ASP015K, JNJ-54781532)Subtitle: JAK inhibitorBiological Activity: SMLES: N=C(O)C1=CNC2=NC=CC2=C1N3()(C4)()C5()C3()C4(O)C5CAS NO: 1821908-48-8Standard In CHIKey: Others inhibitorsStandard InChI: Typrof Compound: Appearance: Formula: C18H22N4O2M.Wt: 326.39General Tips: For obtaining a higher solubility ,…
Product Name: PX-478 2HClSubtitle: HIF-1α inhibitorBiological Activity: SMLES: ClCC(C1=CC=C(C(N)()C(O)=O)C=C1)()CCCl.Cl.ClCAS NO: 1190932-38-7Standard In CHIKey: Acids and Aldehydes inhibitorsStandard InChI: Typrof Compound: Appearance: Formula: C13H20Cl4N2O3M.Wt: 394.12General Tips: For obtaining a higher solubility…
Product Name: GSK2801Subtitle: inhibitor of BAZ2A and BAZ2B bromodomainsBiological Activity: Biological Activity of GSK2801Selective BAZ2A and BAZ2B inhibitor (IC50 values are 0.40 and 0.43 μM, respectively). Selective for BAZ2A/B over…