Product Name: MevastatinSubtitle: HMG-CoA reductase inhibitorBiological Activity: Biological Activity of Mevastatin Inhibitor of HMG-CoA reductase; decreases cholesterol biosynthesis, in vitro and in vivo. Induces apoptosis, arrests cancer cells in G1…
Product Name: LovastatinSubtitle: HMG-CoA reductase inhibitorBiological Activity: Biological Activity of Lovastatin Potent, competitive inhibitor of HMG-CoA reductase (Ki = 0.6 nM) therefore decreases cholesterol biosynthesis, in vitro and in vivo.…
Product Name: EzetimibeSubtitle: Cholesterol transport inhibitorBiological Activity: Biological Activity of Ezetimibe 1. Ezetimibe is known as a Niemann-Pick C1-Like 1 (NPC1L1) inhibitor and has been used as an agent for…
Product Name: DiosmetinSubtitle: CYP1A1 inhibitorBiological Activity: Biological Activity of Diosmetin 1. Diosmetin has anti-inflammatory and antioxidant properties. 2. Diosmetin has beneficial effect on the course of cerulein-induced AP in mice.…
Product Name: AlizarinSubtitle: Biological stainBiological Activity: Biological Activity of Alizarin 1. Alizarin has a selective and effective inhibitory activity towards cancerous cells. 2. Alizarin acts through the inhibition of ERK…
Product Name: Abiraterone AcotateSubtitle: Cytochrome p450 17a1 inhibitorBiological Activity: SMLES: CC(=O)O1CC2(C)C3CC4(C)C(CC=C4c5cccnc5)C3CC=C2C1CAS NO: 147536-97-8Standard In CHIKey: UVIQSJCZCSLXRZ-HMMZIKKISA-NHistone Demethylase inhibitorsStandard InChI: InChI=1S/C26H33NO2/c1-17(28)29-20-10-12-25(2)19(15-20)6-7-21-23-9-8-22(18-5-4-14-27-16-18)26(23,3)13-11-24(21)25/h4-6,8,14,16,20-21,23-24H,7,9-13,15H2,1-3H3/t20-,21?,23?,24?,25-,26+/m0/s1Typrof Compound: AlkaloidsAppearance: PowderFormula: C26H33NO2M.Wt: 391.55General Tips: For obtaining a higher…
Product Name: CMPD-1Subtitle: Biological Activity: Biological Activity of CMPD-1Non-ATP-competitive, selective inhibitor of p38α-mediated MK2a (mitogen-activated protein kinase-2a) phosphorylation (apparent Ki = 330 nM). Does not inhibit p38α-mediated phosphorylation of MBP…
Product Name: SKF 86002 dihydrochlorideSubtitle: Biological Activity: Biological Activity of SKF 86002 dihydrochlorideInhibitor of p38 MAP kinase (IC50 = 0.1 – 1 μM). Potently inhibits LPS-induced IL-1 and TNF-α production…
Product Name: U0124Subtitle: Biological Activity: Biological Activity of U0124Inactive analog of U0126. Used as a negative control. Does not inhibit MEK at concentrations up to 100 μM.SMLES: N/C(SC)=C(C#N)C(C#N)=C(N)SCCAS NO: 1616632-77-9Standard…
Product Name: AnisomycinSubtitle: JNK agonist, potent and specificBiological Activity: Biological Activity of AnisomycinProtein synthesis inhibitor (blocks translation). Potent activator of stress-activated protein kinases (JNK/SAPK) and p38 MAP kinase. Acts as…