Product Name: SalirasibSubtitle: Inhibitor of active Ras proteinBiological Activity: Biological Activity of SalirasibInhibitor of active Ras proteins. Displaces active Ras from the plasma membrane; impairs downstream signaling and inhibits proliferation…
Product Name: MLN 2480Subtitle: Pan-Raf kinase inhibitor,investigationalBiological Activity: Biological Activity of MLN 2480Description MLN 2480 is an oral, selective inhibitor of Raf kinases. Targets Raf kinases IC50SMLES: CC(C1=NC=C(S1)C(=O)NC2=NC=C(C(=C2)C(F)(F)F)Cl)NC(=O)C3=C(C(=NC=N3)N)ClCAS NO: 530141-72-1Standard…
Product Name: MEK inhibitorSubtitle: Potent MEK inhibitor, Antitumor agentBiological Activity: SMLES: CNC(=O)C1=CC2=C(C=C1)C(=C(C3=CC=CC=C3)NC4=CC=CC(=C4)CN(C)C)C(=O)N2CAS NO: 1352608-82-2Standard In CHIKey: Filovirus inhibitorsStandard InChI: Typrof Compound: Appearance: Formula: C26H26N4O2M.Wt: 426.51General Tips: For obtaining a higher…
Product Name: JNK-IN-8Subtitle: JNK inhibitor, selective and irreversibleBiological Activity: Biological Activity of JNK-IN-8Description JNK-IN-8 is a selective and irreversible type 2 inhibitor of JNK with IC50 value of 4.67 nM,…
Product Name: JNK-IN-7Subtitle: Selective JNK inhibitorBiological Activity: SMLES: CN(C)C/C=C/C(=O)Nc1cccc(c1)C(=O)Nc2ccc(cc2)Nc3nccc(n3)c4cccnc4CAS NO: 1262238-11-8Standard In CHIKey: Bacterial inhibitorsStandard InChI: Typrof Compound: Appearance: Formula: C28H27N7O2M.Wt: 493.56General Tips: for obtaining a higher concentration: Please warm…
Product Name: DB07268Subtitle: JNK1 inhibitorBiological Activity: SMLES: c1ccc(c(c1)C(=O)N)Nc2ccnc(n2)Nc3cccc(c3)OCAS NO: 698394-73-9Standard In CHIKey: Arenavirus inhibitorsStandard InChI: Typrof Compound: Appearance: Formula: C17H15N5O2M.Wt: 321.33General Tips: For obtaining a higher solubility , please warm…
Product Name: Dabrafenib Mesylate (GSK-2118436)Subtitle: Inhibitor of BRAF(V600) mutantsBiological Activity: Biological Activity of Dabrafenib Mesylate (GSK-2118436) Targets Raf IC50 3.2/0.8/5.0 nM (B-Raf/B-RafV600E/ c-Raf)SMLES: CC(C)(C)c1nc(c(s1)c2ccnc(n2)N)c3cccc(c3F)NS(=O)(=O)c4c(cccc4F)F.CS(=O)(=O)OCAS NO: 1192491-61-4Standard In CHIKey: Anti-infection inhibitorsStandard…
Product Name: Cobimetinib (R-enantiomer)Subtitle: Selective MEK inhibitorBiological Activity: SMLES: C1CCNC(C1)C2(CN(C2)C(=O)C3=C(C(=C(C=C3)F)F)NC4=C(C=C(C=C4)I)F)OCAS NO: 1474110-21-8Standard In CHIKey: Others inhibitorsStandard InChI: Typrof Compound: Appearance: Formula: C21H21F3IN3O2M.Wt: 531.31General Tips: For obtaining a higher solubility ,…
Product Name: Cobimetinib (racemate)Subtitle: Selective MEK inhibitorBiological Activity: SMLES: C1CCNC(C1)C2(CN(C2)C(=O)C3=C(C(=C(C=C3)F)F)NC4=C(C=C(C=C4)I)F)OCAS NO: 915363-56-3Standard In CHIKey: Acids and Aldehydes inhibitorsStandard InChI: Typrof Compound: Appearance: Formula: C21H21F3IN3O2M.Wt: 531.31General Tips: For obtaining a higher…
Product Name: CobimetinibSubtitle: Selective MEK inhibitorBiological Activity: SMLES: c1c(cc(c(c1)Nc2c(c(ccc2C(=O)N3C(C3)(O)4NCCCC4)F)F)F)ICAS NO: 1032350-13-2Standard In CHIKey: Alkaloid inhibitorsStandard InChI: Typrof Compound: Appearance: Formula: C21H21F3IN3O2M.Wt: 531.31General Tips: For obtaining a higher solubility , please…