Grifolic acid
Product Name: Grifolic acidSubtitle: Biological Activity: Biological Activity of Grifolic acid Selective partial FFA4 (GPR120) agonist. Induces ERK and i responses in cells expressing GPR120, but not those expressing GPR40.SMLES:…
Fingolimod hydrochloride
Product Name: Fingolimod hydrochlorideSubtitle: S1P receptors agonistBiological Activity: Biological Activity of Fingolimod hydrochloride 1. Fingolimod hydrochloride is an effective treatment for relapsing MS, is generally well tolerated. 2. Additional information…
Corticosterone
Product Name: CorticosteroneSubtitle: Biological Activity: Biological Activity of Corticosterone Endogenous glucocorticoid that acts as an agonist at glucocorticoid and mineralocorticoid receptors.SMLES: C12C(O)3(CCC4=CC(=O)CC34C)1CC2C(=O)COCAS NO: 857066-90-1Standard In CHIKey: OMFXVFTZEKFJBZ-HJTSIMOOSA-NiGluR inhibitorsStandard InChI: InChI=1S/C21H30O4/c1-20-8-7-13(23)9-12(20)3-4-14-15-5-6-16(18(25)11-22)21(15,2)10-17(24)19(14)20/h9,14-17,19,22,24H,3-8,10-11H2,1-2H3/t14-,15-,16+,17-,19+,20-,21-/m0/s1Typrof…
Adrenaline
Product Name: AdrenalineSubtitle: Biological Activity: Biological Activity of Adrenaline 1. Less frequent average epinephrine dosing than recommended by consensus guidelines was associated with improved survival of in-hospital cardiac arrest. 2.…
DMOG
Product Name: DMOGSubtitle: Competitive HIF-PH inhibitor, cell-permeableBiological Activity: Biological Activity of DMOGProlyl 4-hydroxylase (P4H) inhibitor; inhibits hypoxia-inducible factor α (HIF-α) prolyl hydroxylase (HIF-PH). Increases levels of HIF-1α; promotes cell survival…
Chetomin
Product Name: ChetominSubtitle: A4505 inhibitorBiological Activity: SMLES: O=C((N1C)(SS2)CC3=CN((4()N5)(C6(SS7)N4C(7(CO)N(C)C6=O)=O)C8=C5C=CC=C8)C9=C3C=CC=C9)N(C)2(CO)C1=OCAS NO: 915019-65-7Standard In CHIKey: ZRZWBWPDBOVIGQ-UHFFFAOYSA-NGABA Receptor inhibitorsStandard InChI: InChI=1S/C31H30N6O6S4/c1-33-25(42)30(15-38)34(2)23(40)28(33,44-46-30)12-17-13-36(21-11-7-4-8-18(17)21)27-14-29-24(41)35(3)31(16-39,47-45-29)26(43)37(29)22(27)32-20-10-6-5-9-19(20)27/h4-11,13,22,32,38-39H,12,14-16H2,1-3H3Typrof Compound: Appearance: Formula: C31H30N6O6S4M.Wt: 710.87General Tips: For obtaining a higher solubility , please…
UNC 0646
Product Name: UNC 0646Subtitle: G9a and GLP inhibitorBiological Activity: Biological Activity of UNC 0646Potent and selective inhibitor of the homologous protein lysine methyltransferases, G9a and GLP (IC50 values are 6…
UNC 0224
Product Name: UNC 0224Subtitle: G9a histone methyltransferase inhibitorBiological Activity: Biological Activity of UNC 0224Potent G9a and GLP inhibitor (IC50 values are 15 and 20 nM in a ThioGlo assay, respectively).…
Chaetocin
Product Name: ChaetocinSubtitle: SUV39H1 InhibitorBiological Activity: SMLES: O=C1(CO)(SS2)N(C)C(32N14()(C(C=CC=C5)=C5N4)(6(C(C=CC=C7)=C7N8)8()N(C((CO)(SS9)N%10C)=O)9(C6)C%10=O)C3)=OCAS NO: 23109-05-9Standard In CHIKey: PZPPOCZWRGNKIR-UHFFFAOYSA-NCRAC Channel inhibitorsStandard InChI: InChI=1S/C30H28N6O6S4/c1-33-21(39)27-11-25(15-7-3-5-9-17(15)31-19(25)35(27)23(41)29(33,13-37)45-43-27)26-12-28-22(40)34(2)30(14-38,46-44-28)24(42)36(28)20(26)32-18-10-6-4-8-16(18)26/h3-10,19-20,31-32,37-38H,11-14H2,1-2H3Typrof Compound: Appearance: Formula: C30H28N6O6S4M.Wt: 696.84General Tips: For obtaining a higher solubility , please…
SGC-CBP30
Product Name: SGC-CBP30Subtitle: Inhibitor of CREBBP/EP300 bromodomain,potentBiological Activity: Biological Activity of SGC-CBP30Description SGC-CBP30 is a potent inhibitor of CREBBP/EP300 with IC50 values of 21 nM and 38 nM, respectively. Targets…