Product Name: Tofacitinib (CP-690550,Tasocitinib)Subtitle: Janus kinase inhibitorBiological Activity: SMLES: CC1CCN(CC1N(C)C2=NC=NC3=C2C=CN3)C(=O)CC#NCAS NO: 1208313-97-6Standard In CHIKey: COX inhibitorsStandard InChI: Typrof Compound: Appearance: Formula: C16H20N6OM.Wt: 312.37General Tips: For obtaining a higher solubility ,…
Product Name: AZD1480Subtitle: JAK2 inhibitor,ATP-competitive and novelBiological Activity: Biological Activity of AZD1480Potent and selective JAK2 inhibitor (IC50 < 3 nM). Exhibits >50-fold selectivity for JAK2 over JAK3. Exhibits antitumor effects…
Product Name: TG101348 (SAR302503)Subtitle: JAK-2 inhibitor,potent and selectiveBiological Activity: Biological Activity of TG101348 (SAR302503)Description TG-101348 (SAR302503) is a selective inhibitor of JAK2 with IC50 of 3 nM, 35- and 334-fold…
Product Name: Tofacitinib (CP-690550) CitrateSubtitle: Potent JAK inhibitorBiological Activity: Biological Activity of Tofacitinib (CP-690550) CitrateDescription Tofacitinib (CP-690550) Citrate is a novel inhibitor of JAK3 with IC50 of 1 nM, 20-…
Product Name: CCT137690Subtitle: Aurora A/B/C inhibitorBiological Activity: Biological Activity of CCT137690Potent inhibitor of Aurora kinases (IC50 values are 0.015, 0.019 and 0.025 μM at Aurora A, Aurora C and Aurora…
Product Name: CCT129202Subtitle: Aurora kinase inhibitor,ATP-competitive and potentBiological Activity: Biological Activity of CCT129202Description CCT129202 is an inhibitor of Aurora kinases with IC50 values of 42 nM, 198 nM and 227…
Product Name: ENMD-2076Subtitle: Selective Aurora A/Flt3 inhibitorBiological Activity: Biological Activity of ENMD-2076Description ENMD-2076 is a selective inhibitor of Aurora A and Flt3 with IC50 values of 14 nM and 1.86…
Product Name: ENMD-2076 L-(+)-Tartaric acidSubtitle: Aurora kinases inhibitorBiological Activity: SMLES: CC1=CC(=NN1)NC2=NC(=NC(=C2)N3CCN(CC3)C)C=CC4=CC=CC=C4.C(C(C(=O)O)O)(C(=O)O)OCAS NO: 1228690-19-4Standard In CHIKey: RGS Protein inhibitorsStandard InChI: Typrof Compound: Appearance: Formula: C25H31N7O6M.Wt: 525.56General Tips: For obtaining a higher…
Product Name: PF-03814735Subtitle: Aurora A/B inhibitorBiological Activity: Biological Activity of PF-03814735ATP-competitive inhibitor of Aurora kinases A and B (IC50 values are 0.8 and 5 nM for recombinant Aurora B and…
Product Name: GSK1070916Subtitle: Aurora B/C inhibitorBiological Activity: Biological Activity of GSK1070916Description GSK1070916 is a reversible and ATP-competitive inhibitor of Aurora B and C with IC50 value of 3.5 nM and…