Product Name: JNJ-7706621Subtitle: Potent CDK/Aurora kinase inhibitorBiological Activity: Biological Activity of JNJ-7706621Description JNJ-7706621 is a potent inhibitor of cyclin-dependent kinases (CDK) and Aurora kinases with IC50 values of 9 nM,…
Product Name: MLN8054Subtitle: Aurora A inhibitorBiological Activity: Biological Activity of MLN8054Description MLN8054 is an oral, ATP-competitive, selective small-molecule inhibitor of Aurora A with IC50 value of 4 nM. Targets Aurora…
Product Name: ZM 447439Subtitle: Aurora Kinase inhibitor,potent and selectiveBiological Activity: Biological Activity of ZM 447439Novel, selective ATP-competitive inhibitor of Aurora B kinase in vitro (IC50 values are 50, 250 and…
Product Name: Barasertib (AZD1152-HQPA)Subtitle: Aurora Kinase B inhibitor, Potent and selectiveBiological Activity: Biological Activity of Barasertib (AZD1152-HQPA)Description Barasertib (AZD1152-HQPA) is a highly selective inhibitor of Aurora B with IC50 of…
Product Name: VX-680 (MK-0457,Tozasertib)Subtitle: Aurora kinase inhibitorBiological Activity: Biological Activity of VX-680 (MK-0457,Tozasertib)High affinity and selective Aurora kinase inhibitor (Ki values are 0.6, 5 and 18 nM for Aurora A,…
Product Name: MLN8237 (Alisertib)Subtitle: Aurora A Kinase inhibitor, Potent and selectiveBiological Activity: Biological Activity of MLN8237 (Alisertib)Description Alisertib (MLN8237) is a selective inhibitor of Aurora A with IC50 of 1.2…
Product Name: AZD1208Subtitle: PIM kinase inhibitorBiological Activity: Biological Activity of AZD1208Description AZD1208 is a potent, and orally available inhibitor of Pim kinase with IC50 values of 0.4 nM, 5 nM,…
Product Name: Veliparib dihydrochlorideSubtitle: PARP-1/PARP-2 inhibitorBiological Activity: Biological Activity of Veliparib dihydrochlorideVeliparib (ABT-888) is a potent inhibitor of PARP1 and PARP2 with Ki of 5.2 nM and 2.9 nM, respectively.…
Product Name: XL228Subtitle: IGF1R/AURORA /FGFR1-3/ABL/SRC family kinases inhibitorBiological Activity: SMLES: CC(C)C1=NOC(=C1)CNC2=NC(=CC(=N2)NC3=NNC(=C3)C4CC4)N5CCN(CC5)CCAS NO: 0Standard In CHIKey: Guanylate Cyclase inhibitorsStandard InChI: Typrof Compound: Appearance: Formula: C22H31N9OM.Wt: 437.54General Tips: For obtaining a higher…
Product Name: XL019Subtitle: JAK2 inhibitor,potent and selectiveBiological Activity: Biological Activity of XL019Description XL019 is a potent and selective inhibitor of JAK2 with IC50 value of 2.2 nM. Targets JAK2 IC50…