Product Name: OTX-015Subtitle: BRD inhibitorBiological Activity: Biological Activity of OTX-015Description OTX-015 is an orally bioavailable and small molecule inhibitor of bromodomain and extra terminal domain (BET) family proteins with EC50…
Product Name: NVP-BSK805Subtitle: ATP-competitive JAK2 inhibitorBiological Activity: Biological Activity of NVP-BSK805Description NVP-BSK805 is a potent and selective ATP-competitive inhibitor of JAK2 with IC50 of 0.5 nM,>20-fold selectivity towards JAK1, JAK3…
Product Name: MK-4827Subtitle: PARP-1/-2 inhibitor,potent and selectiveBiological Activity: Biological Activity of MK-4827MK-4827 is a potent, selective inhibitor of PARP 1 and PARP 2 with IC50 of 3.8 and 2.1 nM,…
Product Name: LKB1 (AAK1 dual inhibitor)Subtitle: Pim-1 kinase inhibitorBiological Activity: SMLES: c1cc(cnc1)C(=O)Nc2cc3c2cc(cn3)c4ccc(cc4)C#NCAS NO: 594839-88-0Standard In CHIKey: Dopamine Receptor inhibitorsStandard InChI: Typrof Compound: Appearance: Formula: C20H13N5OM.Wt: 339.36General Tips: For obtaining a…
Product Name: JANEX-1Subtitle: JAK3 inhibitorBiological Activity: SMLES: COc1cc2c(cc1OC)ncnc2Nc3ccc(cc3)OCAS NO: 701977-09-5Standard In CHIKey: CXCR inhibitorsStandard InChI: Typrof Compound: Appearance: Formula: C16H15N3O3M.Wt: 297.31General Tips: For obtaining a higher solubility , please warm…
Product Name: JAK2 Inhibitor V, Z3Subtitle: Jak2 tyrosine kinase inhibitorBiological Activity: SMLES: CC(CCC1=CC=CC=N1)(CCC2=CC=CC=N2)C(=O)C3=CC=CC=C3CAS NO: 1445993-26-9Standard In CHIKey: CRTH2 GPR44) inhibitorsStandard InChI: Typrof Compound: Appearance: Formula: C23H24N2OM.Wt: 344.45General Tips: For obtaining…
Product Name: GSK 525768ASubtitle: inactive stereoisomer of I-BET-762Biological Activity: SMLES: CCNC(=O)CC1C2=NN=C(N2C3=C(C=C(C=C3)OC)C(=N1)C4=CC=C(C=C4)Cl)CCAS NO: 956697-53-3Standard In CHIKey: Cholecystokinin Receptor inhibitorsStandard InChI: Typrof Compound: Appearance: Formula: C22H22ClN5O2M.Wt: 423.9General Tips: For obtaining a higher…
Product Name: CYT387 sulfate saltSubtitle: JAK1/JAK2 inhibitorBiological Activity: SMLES: C1COCCN1C2=CC=C(C=C2)NC3=NC=CC(=N3)C4=CC=C(C=C4)C(=O)NCC#N.OS(=O)(=O)O.OS(=O)(=O)OCAS NO: 129-56-6Standard In CHIKey: CGRP Receptor inhibitorsStandard InChI: Typrof Compound: Appearance: Formula: C23H26N6O10S2M.Wt: 610.62General Tips: For obtaining a higher solubility…
Product Name: CX-6258 hydrochloride hydrateSubtitle: Pan-Pim kinases InhibitorBiological Activity: SMLES: CC1=CN=C(C=N1)CNC(=O)C2=C3N(C4=CC=CC=C4S3)C5=C(C2=O)C=CC(=N5)N6CCCN(CC6)CCAS NO: 441045-17-6Standard In CHIKey: CCR inhibitorsStandard InChI: Typrof Compound: Appearance: Formula: C26H27Cl2N3O4M.Wt: 516.42General Tips: For obtaining a higher solubility…
Product Name: CX-6258Subtitle: Pan-Pim kinases InhibitorBiological Activity: Biological Activity of CX-6258Description CX-6258 HCl is a potent, orally efficacious inhibitor of pan-Pim kinase with IC50 of 5 nM, 25 nM and…