Product Name: CX-6258 hydrochloride hydrateSubtitle: Pan-Pim kinases InhibitorBiological Activity: SMLES: CC1=CN=C(C=N1)CNC(=O)C2=C3N(C4=CC=CC=C4S3)C5=C(C2=O)C=CC(=N5)N6CCCN(CC6)CCAS NO: 441045-17-6Standard In CHIKey: CCR inhibitorsStandard InChI: Typrof Compound: Appearance: Formula: C26H27Cl2N3O4M.Wt: 516.42General Tips: For obtaining a higher solubility…
Product Name: CX-6258Subtitle: Pan-Pim kinases InhibitorBiological Activity: Biological Activity of CX-6258Description CX-6258 HCl is a potent, orally efficacious inhibitor of pan-Pim kinase with IC50 of 5 nM, 25 nM and…
Product Name: BMN-673 8R,9SSubtitle: PARP inhibitorBiological Activity: Biological Activity of BMN-673 8R,9SBMN 673 is a novel PARP inhibitor with IC50 of 0.58 nM(PARP1). It does not inhibit PARG and is…
Product Name: Baricitinib phosphateSubtitle: JAK1/JAK2 inhibitorBiological Activity: SMLES: CAS NO: 852808-04-9Standard In CHIKey: Bradykinin Receptor inhibitorsStandard InChI: Typrof Compound: Appearance: Formula: C16H20N7O6PSM.Wt: 469.41General Tips: For obtaining a higher solubility ,…
Product Name: Bardoxolone methylSubtitle: IKK inhibitor, potent antioxidant inflammation modulatorBiological Activity: Biological Activity of Bardoxolone methylDescription Bardoxolone methyl is an oral modulator of antioxidant inflammation. Targets antioxidant inflammation IC50SMLES: CAS…
Product Name: AZD1152Subtitle: Aurora B kinase inhibitor,highly potent and selectiveBiological Activity: SMLES: CAS NO: 629664-81-9Standard In CHIKey: Angiotensin Receptor inhibitorsStandard InChI: Typrof Compound: Appearance: Formula: C26H31FN7O6PM.Wt: 587.54General Tips: For obtaining…
Product Name: Ruxolitinib (INCB018424)Subtitle: JAK inhibitorBiological Activity: Biological Activity of Ruxolitinib (INCB018424)Description INCB018424 is the first potent, selective inhibitor of JAK1/2 to enter the clinic with IC50 of 3.3 nM/2.8…
Product Name: ABT-888 (Veliparib)Subtitle: Potent PARP inhibitorBiological Activity: Biological Activity of ABT-888 (Veliparib)Veliparib (ABT-888) is a potent inhibitor of PARP1 and PARP2 with Ki of 5.2 nM and 2.9 nM,…
Product Name: ZebularineSubtitle: DNA methylation inhibitorBiological Activity: Biological Activity of ZebularineOrally active DNA methyltransferase inhibitor. Inhibits tumor cell proliferation (IC50 = 120 μM) and re-activates silenced genes in T24 bladder…
Product Name: UNC0638Subtitle: G9a/GLP HMTase inhibitor, potent and selectiveBiological Activity: Biological Activity of UNC0638Description UNC0638 is a potent and selective inhibitor of G9a and GLP HMTase with IC50 values of…