Product Name: Pracinostat (SB939)Subtitle: Pan-HDAC inhibitorBiological Activity: Biological Activity of Pracinostat (SB939)Description Pracinostat (SB939) is a potent inhibitor of HDAC with IC50 of 40-140 nM with exception for HDAC6. Targets…
Product Name: MC1568Subtitle: Class II HDAC inhibitor,potent andBiological Activity: Biological Activity of MC1568Selective inhibitor of class IIa histone deacetylases (HDACs). Exhibits tissue-selective inhibition between members of class II deacetylases in…
Product Name: ITF2357 (Givinostat)Subtitle: HDAC inhibitorBiological Activity: Biological Activity of ITF2357 (Givinostat)Description Givinostat (ITF2357) is a potent inhibitor of HDAC for maize HD2, HD1B and HD1A with IC50 of 10…
Product Name: CUDC-101Subtitle: Multitargeted HDAC inhibitorBiological Activity: Biological Activity of CUDC-101Description CUDC-101 is a potent inhibitor of HDAC, EGFR and HER2 with IC50 values of 4.4 nM, 2.4 nM, and…
Product Name: PCI-34051Subtitle: HDAC8 inhibitor,potent and selectiveBiological Activity: Biological Activity of PCI-34051Potent and selective histone deacetylase 8 (HDAC8) inhibitor (IC50 = 10 nM). Displays >200 fold selectivity over HDAC isoforms…
Product Name: JNJ-26481585Subtitle: Potent HDAC inhibitorBiological Activity: Biological Activity of JNJ-26481585Description Quisinostat (JNJ-26481585) is a novel second-generation inhibitor of HDAC with highest potency for HDAC1 with IC50 of 0.11 nM.…
Product Name: Mocetinostat (MGCD0103, MG0103)Subtitle: HDAC inhibitor,isotype-selective and potentBiological Activity: Biological Activity of Mocetinostat (MGCD0103, MG0103)Description Mocetinostat (MGCD0103) is a potent inhibitor of HDAC with most potency for HDAC1 with…
Product Name: Vorinostat (SAHA, MK0683)Subtitle: HDAC inhibitorBiological Activity: Biological Activity of Vorinostat (SAHA, MK0683)Inhibits Class I and II histone deacetylases (HDACs); induces accumulation of acetylated histones H2A, H2B, H3 and…
Product Name: Rocilinostat (ACY-1215)Subtitle: Selective HDAC6 inhibitorBiological Activity: Biological Activity of Rocilinostat (ACY-1215)Description Rocilinostat (ACY-1215) is a selective inhibitor of HDAC6 with IC50 of 5 nM. Targets HDAC6 IC50 5…
Product Name: DoxorubicinSubtitle: Topo II inhibitor,immunosuppresive antineoplastic antibioticBiological Activity: Biological Activity of DoxorubicinDescription Doxorubicin (Adriamycin) is an antibiotic agent, inhibitor of DNA topoisomerase II and inducer of DNA damage and…