Product Name: DoxorubicinSubtitle: Topo II inhibitor,immunosuppresive antineoplastic antibioticBiological Activity: Biological Activity of DoxorubicinDescription Doxorubicin (Adriamycin) is an antibiotic agent, inhibitor of DNA topoisomerase II and inducer of DNA damage and…
Product Name: Voreloxin HydrochlorideSubtitle: Antineoplastic naphthyridine analogueBiological Activity: SMLES: CNC1CN(CC1OC)C2=NC3=C(C=C2)C(=O)C(=CN3C4=NC=CS4)C(=O)O.ClCAS NO: 159351-69-6Standard In CHIKey: Porcupine inhibitorsStandard InChI: Typrof Compound: Appearance: Formula: C18H20ClN5O4SM.Wt: 437.9General Tips: For obtaining a higher solubility ,…
Product Name: VoreloxinSubtitle: Topo II inhibitorBiological Activity: Biological Activity of VoreloxinDescription Voreloxin is an inhibitor of topoisomerase II. Targets topoisomerase II IC50SMLES: CNC1CN(CC1OC)C2=NC3=C(C=C2)C(=O)C(=CN3C4=NC=CS4)C(=O)OCAS NO: 574013-66-4Standard In CHIKey: Oct3_4 inhibitorsStandard InChI:…
Product Name: VAL-083Subtitle: Bi-functional alkylating agentBiological Activity: Biological Activity of VAL-083Description VAL-083 is a structurally unique first-in-class N7-bifunctional alkylating agent of DNA. Targets DNA IC50SMLES: C1C(O1)C(C(C2CO2)O)OCAS NO: 182004-65-5Standard In CHIKey:…
Product Name: TH-302Subtitle: Hypoxia-activated prodrug,inhibits H460/HT29 cell growthBiological Activity: Biological Activity of TH-302Description TH-302 is a hypoxia-activated prodrug of the cytotoxin bromo-isophosphoramide mustard (Br-IPM). Targets thioredoxin reductase glutathione reductase IC50SMLES:…
Product Name: TasquinimodSubtitle: Antiangiogenic and antineoplastic agentBiological Activity: Biological Activity of TasquinimodDescription Tasquinimod is an oral antitumor drug. Targets tumor microenvironment IC50SMLES: CN1C2=C(C(=CC=C2)OC)C(=C(C1=O)C(=O)N(C)C3=CC=C(C=C3)C(F)(F)F)OCAS NO: 128517-07-7Standard In CHIKey: Hedgehog inhibitorsStandard InChI:…
Product Name: RG2833Subtitle: Brain-penetrant HDAC inhibitorBiological Activity: Biological Activity of RG2833Description RG2833 is a brain-penetrant inhibitor of HDAC with IC50 values of 60 nM and 50 nM for HDAC1 and…
Product Name: Resminostat hydrochlorideSubtitle: HDAC inhibitorBiological Activity: SMLES: CN(C)CC1=CC=C(S(=O)(N2C=C(/C=CC(NO)=O)C=C2)=O)C=C1.ClCAS NO: 1338545-07-5Standard In CHIKey: Stem Cell_Wnt inhibitorsStandard InChI: Typrof Compound: Appearance: Formula: C16H20ClN3O4SM.Wt: 385.87General Tips: For obtaining a higher solubility ,…
Product Name: PSI-7977Subtitle: Antiviral agents for chronic HCV infectionBiological Activity: Biological Activity of PSI-7977Description PSI-7977 is a phosphoramidate prodrug of PSI-7851. Targets HCV RNA-dependent RNA polymerase IC50 92 nM (EC50)SMLES:…
Product Name: ParadolSubtitle: Active flavor constituent of the seeds of Guinea pepperBiological Activity: SMLES: CCCCCCCC(=O)CCC1=CC(=C(C=C1)O)OCCAS NO: 402567-16-2Standard In CHIKey: CZNLTCTYLMYLHL-UHFFFAOYSA-NTrk Receptor inhibitorsStandard InChI: InChI=1S/C17H26O3/c1-3-4-5-6-7-8-15(18)11-9-14-10-12-16(19)17(13-14)20-2/h10,12-13,19H,3-9,11H2,1-2H3Typrof Compound: Appearance: Formula: C17H26O3M.Wt: 278.39General Tips:…